| Literature DB >> 6259538 |
Abstract
To investigate the sequences necessary for proper initiation of transcription of SV40 early genes, we have constructed several deletion mutants in the promoter region. The TATA box region is apparently involved in fixing initiation precisely within a narrow area, but is dispensable for gene expression, while the sequences located more than 150 base pairs upstream are indispensable.Mesh:
Substances:
Year: 1981 PMID: 6259538 DOI: 10.1038/290304a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962