Literature DB >> 6258969

A postsynaptic alpha 2-receptor: the alpha-adrenergic receptor of hamster white fat cells.

C Carpéné, M Lafontan, M Berlan.   

Abstract

The effects of selected alpha-agonists and alpha-antagonists on theophylline-induces lipolysis were investigate in isolated hamster white fat cells, alpha 2-Agonists (tramazoline, clonidine) inhibited theophylline-induced lipolysis while in alpha 1-agonist (methoxamine) was without any effect. The inhibitory effect of alpha 2-agonists was suppressed by yohimbine (alpha 2-antagonist), whereas alpha 1-antagonists were inefficient. This result implies that the alpha-adrenergic receptor of hamster fat cells is of the alpha 2-type, although postsynaptically.

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Year:  1980        PMID： 6258969     DOI： 10.1007/bf01960132

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Microdetermination of long-chain fatty acids in plasma and tissues.

Authors:  V P DOLE; H MEINERTZ
Journal:  J Biol Chem       Date:  1960-09       Impact factor: 5.157

2.  [Enzymic method for the determination of glycerin].

Authors:  O WIELAND
Journal:  Biochem Z       Date:  1957

3.  Agonist-specific effects of monovalent and divalent cations on adenylate cyclase-coupled alpha adrenergic receptors in rabbit platelets.

Authors:  B S Tsai; R J Lefkowitz
Journal:  Mol Pharmacol       Date:  1978-07       Impact factor: 4.436

4.  Roles of alpha and beta adrenergic receptors in control of glucose oxidation in hamster epididymal adipocytes.

Authors:  R J Schimmel
Journal:  Biochim Biophys Acta       Date:  1976-04-23

Review 5.  Presynaptic receptor systems in catacholamingergic transmission.

Authors:  K Starke; H D Taube; E Browski
Journal:  Biochem Pharmacol       Date:  1977-02-15       Impact factor: 5.858

6.  Preferential blockade of presynaptic alpha-adrenoceptors by yohimbine.

Authors:  K Starke; E Borowski; T Endo
Journal:  Eur J Pharmacol       Date:  1975-12       Impact factor: 4.432

7.  Distinct alpha-noradrenergic receptors differentiated by binding and physiological relationships.

Authors:  D C U'Prichard; S H Snyder
Journal:  Life Sci       Date:  1979-01-01       Impact factor: 5.037

8.  Direct biochemical evidence for the existence of alpha-adrenergic receptors in hamster white adipocyte membranes.

Authors:  R Pecquery; L Malagrida; Y Giudicelli
Journal:  FEBS Lett       Date:  1979-02-15       Impact factor: 4.124

9.  Control of cyclic AMP levels in isolated fat cells from hamsters.

Authors:  K J Hittelman; C F Wu; R W Butcher
Journal:  Biochim Biophys Acta       Date:  1973-03-30

10.  Inhibition of lipolysis in hamster epididymal adipocytes by selective alpha-adrenergic agents. Evidence for cyclic AMP-dependent and independent mechanisms.

Authors:  R J Schimmel
Journal:  Biochim Biophys Acta       Date:  1979-10-04
  10 in total
  1 in total

1.  [3H]-idazoxan binds with high affinity to two sites on hamster adipocytes: an alpha 2-adrenoceptor and a non-adrenoceptor site.

Authors:  A C MacKinnon; C M Brown; M Spedding; A T Kilpatrick
Journal:  Br J Pharmacol       Date:  1989-12       Impact factor: 8.739
  1 in total

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