Literature DB >> 6258575

The inactivation of rat adipocyte Mg2+-dependent phosphatidate phosphohydrolase by noradrenaline.

C H Cheng, E D Saggerson.   

Abstract

The inactivation of rat adipocyte Mg2+-dependent phosphatidate phosphohydrolase by noradrenaline [Cheng & Saggerson (1978) FEBS Lett. 87, 65--68; Cheng & Saggerson (1978) FEBS Lett. 93, 120--124] persists for at least 40 min in crude defatted homogenates kept at 0 degrees C or 20 degrees C, but is diminished at 37 degrees C. The effect of noradrenaline persists through the isolation of post-105000 g supernatants and is then stable in these preparations at 0 degrees C and 37 degrees C. Inclusion of albumin (10--20 mg/ml) in homogenization buffers abolishes the effect of noradrenaline. The effect of noradrenaline is not removed by dialysis of extracts or by raising the concentrations of Mg2+ or phosphatidate in assays.

Entities:  

Mesh:

Substances:

Year:  1980        PMID: 6258575      PMCID: PMC1162144          DOI: 10.1042/bj1900659

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  7 in total

1.  METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS.

Authors:  M RODBELL
Journal:  J Biol Chem       Date:  1964-02       Impact factor: 5.157

2.  Rapid antagonistic actions of noradrealine and insulin on rat adipocyte phosphatidate phosphohydrolase activity.

Authors:  C H Cheng; E D Saggerson
Journal:  FEBS Lett       Date:  1978-09-01       Impact factor: 4.124

3.  Rapid effects of noradrenaline on Mg2+-dependent phosphatidate phosphohydrolase activity in rat adipocytes.

Authors:  C H Cheng; E D Saggerson
Journal:  FEBS Lett       Date:  1978-03-01       Impact factor: 4.124

4.  The regulation of glyceride synthesis from pyruvate in isolated fat cells. The effects of palmitate and alteration of dietary status.

Authors:  E D Saggerson; G Tomassi
Journal:  Eur J Biochem       Date:  1971-11-11

5.  Soluble rat adipocyte phosphatidate phosphatase activity: characterization and effects of fasting and various lipids.

Authors:  F Moller; P Green; E J Harkness
Journal:  Biochim Biophys Acta       Date:  1977-02-23

6.  The intracellular localization of enzymes in white-adipose-tissue fat-cells and permeability properties of fat-cell mitochondria. Transfer of acetyl units and reducing power between mitochondria and cytoplasm.

Authors:  B R Martin; R M Denton
Journal:  Biochem J       Date:  1970-05       Impact factor: 3.857

7.  Glycerolipid synthesis in rat adipose tissue. II. Properties and distribution of phosphatidate phosphatase.

Authors:  S C Jamdar; H J Fallon
Journal:  J Lipid Res       Date:  1973-09       Impact factor: 5.922

  7 in total
  7 in total

1.  A protein tyrosine kinase associated with the ATP-dependent inactivation of adipose diacylglycerol acyltransferase.

Authors:  T E Lau; M A Rodriguez
Journal:  Lipids       Date:  1996-03       Impact factor: 1.880

2.  A kinetic study of glycerophosphate acyltransferase of rat adipocytes in relation to its control by noradrenaline.

Authors:  B Lederer; H G Hers
Journal:  Biochem J       Date:  1985-02-15       Impact factor: 3.857

Review 3.  A partial view of the mechanism of insulin action.

Authors:  R M Denton; R W Brownsey; G J Belsham
Journal:  Diabetologia       Date:  1981-10       Impact factor: 10.122

4.  Adipose-tissue Mg2+-dependent phosphatidate phosphohydrolase. Control of activity and subcellular distribution in vitro and in vivo.

Authors:  S J Taylor; E D Saggerson
Journal:  Biochem J       Date:  1986-10-15       Impact factor: 3.857

5.  Reversible inactivation by noradrenaline of long-chain fatty acyl-CoA synthetase in rat adipocytes.

Authors:  M Hall; E D Saggerson
Journal:  Biochem J       Date:  1985-02-15       Impact factor: 3.857

6.  Regulation by noradrenaline of the mitochondrial and microsomal forms of glycerol phosphate acyltransferase in rat adipocytes.

Authors:  M H Rider; E D Saggerson
Journal:  Biochem J       Date:  1983-07-15       Impact factor: 3.857

7.  Rapid modulation of adipocyte phosphofructokinase activity by noradrenaline and insulin.

Authors:  S R Sooranna; E D Saggerson
Journal:  Biochem J       Date:  1982-03-15       Impact factor: 3.857

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.