Literature DB >> 6257187

Regulation of LH/HCG receptors during the ovarian cycle in rats.

U Müller, T Bauknecht, J W Siebers.   

Abstract

The number of LH/HCG receptors varied during the ovarian cycle. Most 125I-HCG was bound in the diestrous II stage, least amounts of free binding sites were detectable in estrous. Bromocriptine, an inhibitor of prolactin secretion, suppressed the cyclic variations in free LH/HCG receptors. From this finding it is concluded that LH/HCG receptors of the corpus luteum of the cycle are occupied by LH just once and then degraded. The variations in the number of free LH/HCG receptors are probably due to the synthesis and degradation of only luteal receptors.

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Year:  1980        PMID： 6257187     DOI： 10.1007/bf02108268

Source DB:  PubMed          Journal:  Arch Gynecol        ISSN： 0170-9925


  17 in total

1.  Gonadotropin receptors in rat ovarian tissue: III. Binding sites for luteinizing hormone and differentiation of granulosa cells to luteal cells.

Authors:  H J Rajaniemi; A R Midgley; J A Duncan; L E Reichert
Journal:  Endocrinology       Date:  1977-09       Impact factor: 4.736

2.  Effect of gonadotropin-induced receptor regulation on biological responses of isolated rat luteal cells.

Authors:  M Conti; J P Harwood; M L Dufau; K J Catt
Journal:  J Biol Chem       Date:  1977-12-25       Impact factor: 5.157

3.  Autoradiographic analysis of gonadotropin binding to rat ovarian tissue sections.

Authors:  A R Midgley
Journal:  Adv Exp Med Biol       Date:  1973       Impact factor: 2.622

4.  Effect of hypophysectomy on binding of human chorionic gonadotrophin to immature and adult rat ovaries.

Authors:  J W Siebers; W Engel
Journal:  J Endocrinol       Date:  1977-11       Impact factor: 4.286

5.  Regulation of ovarian LH/HCG receptors in immature rats after injection of HCG.

Authors:  J W Siebers
Journal:  Arch Gynecol       Date:  1980

6.  Effect of prolactin on LH receptor in rat luteal cells.

Authors:  J A Holt; J S Richards; A R Midgley; L E Reichert
Journal:  Endocrinology       Date:  1976-04       Impact factor: 4.736

7.  [Inhibition of implantation in the rat due to bromocriptine (author's transl)].

Authors:  J W Siebers; U Müller
Journal:  Arch Gynecol       Date:  1980-01

8.  Binding of human chorionic gonadotrophin to rat ovary during development.

Authors:  J W Siebers; F Peters; M T Zenzes; J Schmidtke; W Engel
Journal:  J Endocrinol       Date:  1977-06       Impact factor: 4.286

9.  Gonadotropin-induced loss of hormone receptors and desensitization of adenylate cyclase in the ovary.

Authors:  M Conti; J P Harwood; A J Hsueh; M L Dufau; K J Catt
Journal:  J Biol Chem       Date:  1976-12-10       Impact factor: 5.157

10.  Ovarian follicular development in the rat: hormone receptor regulation by estradiol, follicle stimulating hormone and luteinizing hormone.

Authors:  J S Richards; J J Ireland; M C Rao; G A Bernath; A R Midgley; L E Reichert
Journal:  Endocrinology       Date:  1976-12       Impact factor: 4.736
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