| Literature DB >> 6255506 |
G J Naylor, A H Smith, E G Dick, D A Dick, A M McHarg, C A Chambers.
Abstract
Erythrocyte Na-K ATPase and sodium pump site numbers were estimated in groups of depressed, manic and recovered patients. The activity of Na-K ATPase per pump site was lower in the depressed group than in the recovered group. In the manic group Na-K ATPase was lower than that of the recovered group, whereas there was no difference in the pump site numbers. In the more severe manics the activity of Na-K ATPase per pump site was significantly lower than that of the recovered patients. Therefore, the change occurring in the erythrocyte membrane cation carrier in manic-depressive psychosis is probably in the activity of individual Na-K ATPase molecules and not in the number of Na-K ATPase molecules per cell.Entities:
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Year: 1980 PMID： 6255506 DOI： 10.1017/s0033291700047413
Source DB: PubMed Journal: Psychol Med ISSN： 0033-2917 Impact factor: 7.723