Literature DB >> 6254017

HLA antigen-related restriction of T lymphocyte cytotoxicity to Epstein-Barr virus.

I S Misko, D J Moss, J H Pope.   

Abstract

The specificity of cytotoxic T cells generated in Epstein-Barr virus (EBV)-infected lymphocyte cultures was investigated, using a 51Cr release assay. Potent cytotoxic T cells with preferred specificity directed to antigens expressed on autologous lymphoblastoid cell line (LCL) target cells were present in 14-day cultures of lymphocytes from EBV-seropositive donors and not from seronegative donors. Moreover, the cytotoxic patterns obtained with a panel of HLA antigen-related and unrelated LCL target cells, supported by unlabeled target inhibition tests, strongly indicate that T cell cytotoxicity to EBV is restricted to HLA antigens.

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Year:  1980        PMID： 6254017      PMCID： PMC349809          DOI： 10.1073/pnas.77.7.4247

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  17 in total

1.  Cytotoxic effector cells specific for B Cell lines transformed by Epstein-Barr virus are present in patients with infectious mononucleosis.

Authors:  E Svedmyr; M Jondal
Journal:  Proc Natl Acad Sci U S A       Date:  1975-04       Impact factor: 11.205

2.  Y-antigen killing by T cells of women is restricted by HLA.

Authors:  E Goulmy; A Termijtelen; B A Bradley; J J van Rood
Journal:  Nature       Date:  1977-04-07       Impact factor: 49.962

3.  Long-term T-cell-mediated immunity to Epstein-Barr virus in man. I. Complete regression of virus-induced transformation in cultures of seropositive donor leukocytes.

Authors:  D J Moss; A B Rickinson; J H Pope
Journal:  Int J Cancer       Date:  1978-12       Impact factor: 7.396

4.  Assay of the infectivity of Epstein-Barr virus by transformation of human leucocytes in vitro.

Authors:  D J Moss; J H Pope
Journal:  J Gen Virol       Date:  1972-11       Impact factor: 3.891

Review 5.  Various forms of Epstein-Barr virus infection in man: established facts and a general concept.

Authors:  M A Epstein; B G Achong
Journal:  Lancet       Date:  1973-10-13       Impact factor: 79.321

6.  A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses.

Authors:  W C Russell; C Newman; D H Williamson
Journal:  Nature       Date:  1975-02-06       Impact factor: 49.962

7.  Human cell-mediated cytotoxicity against modified target cells is restricted by HLA.

Authors:  E Dickmeiss; B Soeberg; A Svejgaard
Journal:  Nature       Date:  1977-12-08       Impact factor: 49.962

8.  HLA restriction of cell-mediated lysis of influenza virus-infected human cells.

Authors:  A J McMichael; A Ting; H J Zweerink; B A Askonas
Journal:  Nature       Date:  1977-12-08       Impact factor: 49.962

9.  Surface markers on human b and t lymphocytes. VI. Cytotoxicity against cell lines as a functional marker for lymphocyte subpopulations.

Authors:  M Jondal; H Pross
Journal:  Int J Cancer       Date:  1975-04-15       Impact factor: 7.396

10.  HLA-linked genetic control of the specicity of human cytotoxic T-cell responses to influenza virus.

Authors:  S Shaw; W E Biddison
Journal:  J Exp Med       Date:  1979-03-01       Impact factor: 14.307
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  27 in total

1.  Functional analysis of the CD4(+) T-cell response to Epstein-Barr virus: T-cell-mediated activation of resting B cells and induction of viral BZLF1 expression.

Authors:  Z Fu; M J Cannon
Journal:  J Virol       Date:  2000-07       Impact factor: 5.103

Review 2.  The immunology of Epstein-Barr virus infection.

Authors:  D J Moss; S R Burrows; S L Silins; I Misko; R Khanna
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2001-04-29       Impact factor: 6.237

3.  Association of HLA Compatibility and Decreased Liver Transplant Survival.

Authors:  B H Markus; R J Duquesnoy; R D Gordon; J J Fung; M Vanek; G Klintmalm; C Bryan; D Van Thiel; T E Starzl
Journal:  Transplant Proc       Date:  1988-02       Impact factor: 1.066

4.  Nonresponsiveness to an immunodominant Epstein-Barr virus-encoded cytotoxic T-lymphocyte epitope in nuclear antigen 3A: implications for vaccine strategies.

Authors:  C Schmidt; S R Burrows; T B Sculley; D J Moss; I S Misko
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-01       Impact factor: 11.205

Review 5.  Adoptive immunotherapy for Epstein-Barr virus-associated lymphoproliferative disorders complicating marrow allografts.

Authors:  R J O'Reilly; T N Small; E Papadopoulos; K Lucas; J Lacerda; L Koulova
Journal:  Springer Semin Immunopathol       Date:  1998

6.  Allospecific T cell recognition of HLA-A2 antigens: evidence for group-specific and subgroup-specific epitopes.

Authors:  L E Wallace; M A Houghton; A B Rickinson; M A Epstein; B A Bradley
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

7.  Generation of specific cytotoxic T cells with a fragment of the Epstein-Barr virus-encoded p63/latent membrane protein.

Authors:  D A Thorley-Lawson; E S Israelsohn
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

8.  Epstein-Barr virus-encoded protein found in plasma membranes of transformed cells.

Authors:  K P Mann; D Staunton; D A Thorley-Lawson
Journal:  J Virol       Date:  1985-09       Impact factor: 5.103

9.  Nucleotide sequence of an mRNA transcribed in latent growth-transforming virus infection indicates that it may encode a membrane protein.

Authors:  S Fennewald; V van Santen; E Kieff
Journal:  J Virol       Date:  1984-08       Impact factor: 5.103

10.  Human leukocyte antigen-linked genetic controls for T cell-mediated cytotoxic response to mumps virus in humans.

Authors:  Y Chiba; H Tsutsumi; T Nakao; A Wakisaka; M Aizawa
Journal:  Infect Immun       Date:  1982-02       Impact factor: 3.441
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