Literature DB >> 6253945

Cloning of V region fragments from mouse liver DNA and localization of repetitive DNA sequences in the vicinity of immunoglobulin gene segments.

M Steinmetz, J Höchtl, H Schnell, W Gebhard, H G Zachau.   

Abstract

Two different kappa light chain genes have previously been isolated from one mouse myeloma. The V (variable, abbreviations in ref. 2) gene segments of the two genes were now used to identify their germline counterparts in EcoRI digests of mouse liver DNA. In addition two sets of related V gene segments were found which hybridize with either of the two DNA probes. Five of the V region fragments of one set were cloned in a lambda phage vector and partially characterized by restriction mapping and Southern blot hybridization. Repetitive DNA sequences were found on each of the five fragments as well as on other cloned immunoglobulin gene containing fragments. Cross-hybridization between some but not all of the regions containing repetitive DNA sequences was observed.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6253945      PMCID： PMC324031          DOI： 10.1093/nar/8.8.1721

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  18 in total

1.  A kappa-immunoglobulin gene is formed by site-specific recombination without further somatic mutation.

Authors:  J G Seidman; E E Max; P Leder
Journal:  Nature       Date:  1979-08-02       Impact factor: 49.962

2.  Cloning of immunoglobulin kappa light chain genes from mouse liver and myeloma MOPC 173.

Authors:  M Steinmetz; H G Zachau; B Mach
Journal:  Nucleic Acids Res       Date:  1979-07-25       Impact factor: 16.971

3.  Sequences of mouse immunoglobulin light chain genes before and after somatic changes.

Authors:  O Bernard; N Hozumi; S Tonegawa
Journal:  Cell       Date:  1978-12       Impact factor: 41.582

4.  DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats.

Authors:  R Lenhard-Schuller; B Hohn; C Brack; M Hirama; S Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

5.  Antibody diversity.

Authors:  J G Seidman; A Leder; M Nau; B Norman; P Leder
Journal:  Science       Date:  1978-10-06       Impact factor: 47.728

6.  Long double-stranded sequences (dsRNA-B) of nuclear pre-mRNA consist of a few highly abundant classes of sequences: evidence from DNA cloning experiments.

Authors:  D A Kramerov; A A Grigoryan; A P Ryskov; G P Georgiev
Journal:  Nucleic Acids Res       Date:  1979-02       Impact factor: 16.971

7.  EK2 derivatives of bacteriophage lambda useful in the cloning of DNA from higher organisms: the lambdagtWES system.

Authors:  P Leder; D Tiemeier; L Enquist
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

8.  Characterization of distinct segments in mouse satellite DNA by restriction nucleases.

Authors:  W Hörz; H G Zachau
Journal:  Eur J Biochem       Date:  1977-03-01

9.  Comparison of cloned mouse alpha- and beta-globin genes: conservation of intervening sequence locations and extragenic homology.

Authors:  A Leder; H I Miller; D H Hamer; J G Seidman; B Norman; M Sullivan; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

10.  Organization of highly repeated sequences in mouse main-band DNA.

Authors:  T R Cech; J E Hearst
Journal:  J Mol Biol       Date:  1976-01-25       Impact factor: 5.469
View more
  16 in total

1.  Specific association of repetitive DNA sequences with major histocompatibility genes.

Authors:  D S Singer; R Lifshitz; L Abelson; P Nyirjesy; S Rudikoff
Journal:  Mol Cell Biol       Date:  1983-05       Impact factor: 4.272

2.  DNA organisation in the chicken lysozyme gene region.

Authors:  P Baldacci; A Royal; F Brégégère; J P Abastado; B Cami; F Daniel; P Kourilsky
Journal:  Nucleic Acids Res       Date:  1981-08-11       Impact factor: 16.971

3.  Two rearranged immunoglobulin kappa light chain genes in one mouse myeloma.

Authors:  M Steinmetz; H G Zachau
Journal:  Nucleic Acids Res       Date:  1980-04-25       Impact factor: 16.971

4.  A short interspersed repetitive element found near some mouse structural genes.

Authors:  K K Lueders; B M Paterson
Journal:  Nucleic Acids Res       Date:  1982-12-11       Impact factor: 16.971

5.  Characterization of X-chromosome specific satellite DNA of Muntiacus muntjak vaginalis.

Authors:  J Bogenberger; H Schnell; F Fittler
Journal:  Chromosoma       Date:  1982       Impact factor: 4.316

6.  Glucocorticoids and chromosomal position modulate murine mammary tumor virus transcription by affecting efficiency of promoter utilization.

Authors:  D S Ucker; G L Firestone; K R Yamamoto
Journal:  Mol Cell Biol       Date:  1983-04       Impact factor: 4.272

7.  Cellular DNA rearrangements and early developmental arrest caused by DNA insertion in transgenic mouse embryos.

Authors:  L Covarrubias; Y Nishida; M Terao; P D'Eustachio; B Mintz
Journal:  Mol Cell Biol       Date:  1987-06       Impact factor: 4.272

8.  A rearranged DNA sequence possibly related to the translocation of immunoglobulin gene segments.

Authors:  M Steinmetz; W Altenburger; H G Zachau
Journal:  Nucleic Acids Res       Date:  1980-04-25       Impact factor: 16.971

9.  Differences in the nuclease sensitivity between the two alleles of the immunoglobulin kappa light chain genes in mouse liver and myeloma nuclei.

Authors:  W O Weischet; B O Glotov; H Schnell; H G Zachau
Journal:  Nucleic Acids Res       Date:  1982-06-25       Impact factor: 16.971

10.  Beta-2 microglobulin types in mice of wild origin.

Authors:  P J Robinson; M Steinmetz; K Moriwaki; K F Lindahl
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.