Literature DB >> 6253667

Factors which disorganize microtubules or microfilaments increase the frequency of cell transformation by polyoma virus.

R Seif.   

Abstract

Griseofulvin, 12-O-tetradecanoyl phorbol-13-acetate, melittin, epidermal growth factor, vinblastine, cytochalasin B, podophyllotoxin, colcemid, and colchicine were unable to transform cells but could increase from 8- to 40-fold the frequency of cell transformation by polyoma virus. The 3T3-like cells were resting at confluence and were exposed to the drug only during the 1st week after viral infection. Griseofulvin, a tumor promoter, reduced or increased the frequency of transformation depending on the dose with which the infected cells were treated. The antitumor activity of tumor promoters is discussed.

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Year:  1980        PMID： 6253667      PMCID： PMC353658     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  52 in total

1.  Antitumor activity in Pimelia simplex.

Authors:  H T Howard; M E Howden
Journal:  Cancer Chemother Rep       Date:  1975 May-Jun

2.  EFFECT OF X-IRRADIATION ON SUSCEPTIBILITY OF CELLS TO TRANSFORMATION BY POLYOMA VIRUS.

Authors:  M STOKER
Journal:  Nature       Date:  1963-11-23       Impact factor: 49.962

3.  Conditions leading to the establishment of the N (a gene dependent) and A (a gene independent) transformed states after polyoma virus infection of rat fibroblasts.

Authors:  M Rassoulzadegan; R Seif; F Cuzin
Journal:  J Virol       Date:  1978-11       Impact factor: 5.103

4.  Factors affecting the frequency of transformation of rat embryo cells by simian virus 40.

Authors:  R Risser; R Pollack
Journal:  Virology       Date:  1979-01-15       Impact factor: 3.616

5.  Antileukemic principles isolated from euphorbiaceae plants.

Authors:  S M Kupchan; I Uchida; A R Branfman; R G Dailey; B Y Fei
Journal:  Science       Date:  1976-02-13       Impact factor: 47.728

6.  The genome of simian virus 40.

Authors:  V B Reddy; B Thimmappaya; R Dhar; K N Subramanian; B S Zain; J Pan; P K Ghosh; M L Celma; S M Weissman
Journal:  Science       Date:  1978-05-05       Impact factor: 47.728

7.  Complete nucleotide sequence of SV40 DNA.

Authors:  W Fiers; R Contreras; G Haegemann; R Rogiers; A Van de Voorde; H Van Heuverswyn; J Van Herreweghe; G Volckaert; M Ysebaert
Journal:  Nature       Date:  1978-05-11       Impact factor: 49.962

8.  Simian virus 40 small t antigen is not required for the maintenance of transformation but may act as a promoter (cocarcinogen) during establishment of transformation in resting rat cells.

Authors:  R Seif; R G Martin
Journal:  J Virol       Date:  1979-12       Impact factor: 5.103

9.  Two-stage chemical oncogenesis in cultures of C3H/10T1/2 cells.

Authors:  S Mondal; D W Brankow; C Heidelberger
Journal:  Cancer Res       Date:  1976-07       Impact factor: 12.701

10.  Simian virus 40 small-t protein is required for loss of actin cable networks in rat cells.

Authors:  A Graessmann; M Graessmann; R Tjian; W C Topp
Journal:  J Virol       Date:  1980-03       Impact factor: 5.103
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  8 in total

Review 1.  An armamentarium of wart treatments.

Authors:  Michelle M Lipke
Journal:  Clin Med Res       Date:  2006-12

2.  Accelerated onset of viral transcription in adenovirus-infected HeLa cells treated with the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate.

Authors:  T H Carter; Z Z Milovanovic; L E Babiss; P B Fisher
Journal:  Mol Cell Biol       Date:  1984-03       Impact factor: 4.272

3.  Cyclic AMP specifically blocks proliferation of rat 3T3 cells transformed by polyomavirus.

Authors:  N Kamech; R Seif; D Pantaloni
Journal:  J Virol       Date:  1987-05       Impact factor: 5.103

4.  Enhanced expression of Epstein-Barr virus early antigens by antitubulin agents in a latently infected human lymphoblastoid cell line.

Authors:  J Fujita; O Yoshida; H Tokuda; K Sugawara; Y Ito
Journal:  Experientia       Date:  1985-03-15

5.  Modulation of adenovirus transformation by thyroid hormone.

Authors:  P B Fisher; D L Guernsey; I B Weinstein; I S Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  1983-01       Impact factor: 11.205

6.  Tumor promoters alter the temporal program of adenovirus replication in human cells.

Authors:  P B Fisher; C S Young; I B Weinstein; T H Carter
Journal:  Mol Cell Biol       Date:  1981-04       Impact factor: 4.272

7.  Rat cells transformed by simian virus 40 give rise to tumor cells which contain no viral proteins and often no viral DNA.

Authors:  R Seif; I Seif; J Wantyghem
Journal:  Mol Cell Biol       Date:  1983-06       Impact factor: 4.272

8.  Generation of metastatic melanoma specific antibodies by affinity purification.

Authors:  Birgit Schütz; Anita Koppensteiner; David Schörghofer; Katharina Kinslechner; Gerald Timelthaler; Robert Eferl; Markus Hengstschläger; Albert Missbichler; Harald Hundsberger; Mario Mikula
Journal:  Sci Rep       Date:  2016-11-17       Impact factor: 4.379
  8 in total

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