Literature DB >> 6252034

Stimulation of pyruvate carboxylation by gastric secretagogues.

E de Bohórquez, J Chacín.   

Abstract

Pyruvate carboxylation was stimulated by 2 gastric secretagogues, histamine and dibutyryl cyclic AMP, and by butyrate. Thiocyanate, an inhibitor of acid secretion, produced a slight decrease. Avidin significantly reduced acid secretion and this effect was overcome by biotin and oxalacetate. The results suggest that carboxylation of pyruvate is one of the reactions controlling oxidative metabolism and acid secretion in toad gastric mucosa.

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Year:  1980        PMID： 6252034     DOI： 10.1007/bf01976126

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  Redox involvement in acid secretion in the amphibian gastric mucosa.

Authors:  E C Rabon; H M Sarau; W S Rehm; G Sachs
Journal:  J Membr Biol       Date:  1977-07-14       Impact factor: 1.843

2.  Metabolic changes associated with gastric stimulation.

Authors:  S J Hersey
Journal:  Gastroenterology       Date:  1977-10       Impact factor: 22.682

3.  Role of oxalacetate in lipoate effect on frog gastric mucosa.

Authors:  J Chacin; O H Park; J B Harris; D Alonso
Journal:  Am J Physiol       Date:  1976-07

4.  Metabolism of dog gastric mucosa. Levels of glycolytic, citric acid cycle and other intermediates.

Authors:  H M Sarau; J J Foley; G Moonsammy; G Sachs
Journal:  J Biol Chem       Date:  1977-12-10       Impact factor: 5.157

5.  Lipoate effect on carbohydrate and lipid metabolism and gastric H+ secretion.

Authors:  J B Harris; D Alonso; O H Park; D Cornfield; J Chacin
Journal:  Am J Physiol       Date:  1975-03

Review 6.  Interactions between oxidative metabolism and acid secretion in gastric mucosa.

Authors:  S J Hersey
Journal:  Biochim Biophys Acta       Date:  1974-09-16

7.  Energy sources for gastric secretion: substrates.

Authors:  D Alonso; K Nigon; I Dorr; J B Harris
Journal:  Am J Physiol       Date:  1967-05

8.  Effect of Krebs cycle intermediates and inhibitors on toad gastric mucosa.

Authors:  J Chacín; R Rincón; D Inciarte; A Cańizales; G Martínez; D Alonso
Journal:  Am J Physiol       Date:  1979-06

9.  Role of fatty acid oxidation in mechanism of action of gastric secretagogues.

Authors:  J Chacín; G Martínez; E Severin
Journal:  Am J Physiol       Date:  1980-03
  9 in total
  1 in total

1.  Effects of gastric secretagogues on tissue glycerol in the isolated amphibian gastric mucosa.

Authors:  G Martínez; J Chacín
Journal:  Experientia       Date:  1985-03-15
  1 in total

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