Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Peripheral infection in culture of rat sensory neurons by herpes simplex virus.

Literature DB >> 6249745

Peripheral infection in culture of rat sensory neurons by herpes simplex virus.

Abstract

The peripheral infection of neurons from dissociated rat sensory ganglia by herpes simplex virus was studied with a newly developed tissue culture system. The results indicated that the virus arrives at the neuronal soma by an axoplasmic route and that at least some of these neurons are productively infected since eventually all cells in the culture appeared to be destroyed by the virus. This system showed promise in elucidating the possible roles of various effector cells, antiviral antibody, or antiviral compounds in the mechanism of herpes simplex virus latency.

Entities: Disease Species

Mesh：

Year: 1980 PMID： 6249745 PMCID： PMC550978 DOI： 10.1128/iai.28.2.620-623.1980

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

20 in total

9. Herpes simplex virus infection of isolated autonomic neurons in culture: viral replication and spread in a neuronal network.

Authors: R W Price; R Rubenstein; A Khan
Journal: Arch Virol Date: 1982 Impact factor: 2.574

10. The interaction of human fetal neurons and epidermal cells in vitro.

Authors: M E Penfold; P J Armati; Z Mikloska; A L Cunningham
Journal: In Vitro Cell Dev Biol Anim Date: 1996 Jul-Aug Impact factor: 2.416

Peripheral infection in culture of rat sensory neurons by herpes simplex virus.

1. Latent ganglionic infection with herpes simplex virus types 1 and 2: viral reactivation in vivo after neurectomy.

2. Study on the propagation of Herpes simplex virus (type 2) into the brain after intraocular injection.

3. Recovery of herpes-simplex virus from human trigeminal ganglions.

4. Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra-axonal transport of infection.

5. Herpes virus latency in spinal ganglia of mice without illness.

6. Recovery of herpes simplex virus from human sacral ganglions.

7. Maintenance of latent herpetic infection: an apparent role for anti-viral IgG.

8. Latent herpes simplex virus in spinal ganglia of mice.

9. Macrophages and age-dependent resistance to Herpes simplex virus in mice.

10. Prevention of cell-to-cell spread of herpes simplex virus by leukocytes.

Review 1. Virus-neuron interaction: an experimental model.

2. Neuron-to-cell spread of pseudorabies virus in a compartmented neuronal culture system.

3. Compartmented neuron cultures for directional infection by alpha herpesviruses.

Review 4. Experimental investigation of herpes simplex virus latency.

5. Herpes simplex virus infection of the rat sensory neuron. Effects of interferon on cultured cells.

6. Herpes simplex virus infection of the human sensory neuron. An electron microscopy study.

7. Rabies virus infection of cultured rat sensory neurons.

8. Neuritic uptake and transport of antiviral drugs modifying herpes simplex virus infection of rat sensory neurons.

9. Herpes simplex virus infection of isolated autonomic neurons in culture: viral replication and spread in a neuronal network.

10. The interaction of human fetal neurons and epidermal cells in vitro.