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Literature DB >> 4364361

Latent ganglionic infection with herpes simplex virus types 1 and 2: viral reactivation in vivo after neurectomy.

Abstract

Inoculation of the cornea, lip, or footpad of mice with herpes simplex virus type 1 resulted in a latent infection of the local sensory ganglia. Inoculation of the vagina and cervix with herpes simplex virus type 2, as well as type 1, also induced a latent ganglionic infection. With the use of sciatic nerve section as a stimulus, a reproducible model of viral reactivation in vivo was established.

Entities: Disease Species

Mesh：

Year: 1974 PMID： 4364361 DOI： 10.1126/science.184.4142.1185

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

57 in total

1. Vaginal formulations of carrageenan protect mice from herpes simplex virus infection.

Authors: V R Zacharopoulos; D M Phillips
Journal: Clin Diagn Lab Immunol Date: 1997-07

2. In vitro system for studying the efficacy of antiviral agents in preventing the reactivation of latent herpes simplex virus.

Authors: C Wohlenberg; H Openshaw; A L Notkins
Journal: Antimicrob Agents Chemother Date: 1979-04 Impact factor: 5.191

3. Latent herpes simplex virus type 1 transcripts in peripheral and central nervous system tissues of mice map to similar regions of the viral genome.

Authors: A M Deatly; J G Spivack; E Lavi; D R O'Boyle; N W Fraser
Journal: J Virol Date: 1988-03 Impact factor: 5.103

Latent ganglionic infection with herpes simplex virus types 1 and 2: viral reactivation in vivo after neurectomy.

1. Vaginal formulations of carrageenan protect mice from herpes simplex virus infection.

2. In vitro system for studying the efficacy of antiviral agents in preventing the reactivation of latent herpes simplex virus.

3. Latent herpes simplex virus type 1 transcripts in peripheral and central nervous system tissues of mice map to similar regions of the viral genome.

4. Characterization of nerve growth factor-dependent herpes simplex virus latency in neurons in vitro.

5. Temperature-sensitive host range mutants of herpes simplex virus type 2.

Review 6. Infectious diseases: fortieth and final annual review of significant publications.

7. Efficacy of phosphonoacetic acid on herpes simplex virus infection of sensory ganglia.

8. Genital herpesvirus hominis infection in mice. I. Development of an experimental model.

9. Temperature-sensitive mutants of herpes simplex virus type 1 defective in lysis but not in transformation.

10. Topical treatment with nerve growth factor in an animal model of herpetic keratitis.