Literature DB >> 6245908

Quantitation of proinsulin mRNA sequences in hamster insulinoma cells in culture by molecular hybridization.

H Yamamoto, K Nose, N Itoh, H Okamoto.   

Abstract

The content of proinsulin mRNA sequences was measured in a cultured cell line established from a transplantable hamster islet cell tumor, by hybridization with proinsulin cDNA. The cells cultured in vitro were found to contain a significant amount of proinsulin mRNA sequences, compared with non-insulin-producing hamster tissues, and seem to be a useful system for the study of insulin gene expression.

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Year:  1980        PMID： 6245908     DOI： 10.1007/bf01953722

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  Purification and characterization of proinsulin mRNA from rat B-cell tumor.

Authors:  N Itoh; K Nose; H Okamoto
Journal:  Eur J Biochem       Date:  1979-06

2.  Inhibition by somatostatin of insulin release from isolated pancreatic islets.

Authors:  H Okamoto; Y Noto; S Miyamoto; H Mabuchi; R Takeda
Journal:  FEBS Lett       Date:  1975-06-01       Impact factor: 4.124

3.  Glucose stimulation of the proinsulin synthesis in isolated pancreatic islets without increasing amount of proinsulin mRNA.

Authors:  N Itoh; T Sei; K Nose; H Okamoto
Journal:  FEBS Lett       Date:  1978-09-15       Impact factor: 4.124

4.  Magnesium precipitation of ribonucleoprotein complexes. Expedient techniques for the isolation of undergraded polysomes and messenger ribonucleic acid.

Authors:  R D Palmiter
Journal:  Biochemistry       Date:  1974-08-13       Impact factor: 3.162

5.  The synthesis and properties of the complete complementary DNA transcript of ovalbumin mRNA.

Authors:  J J Monahan; S E Harris; S L Woo; D L Robberson; B W O'Malley
Journal:  Biochemistry       Date:  1976-01-13       Impact factor: 3.162

6.  Induction of papillary ependymomas and insulinomas in the Syrian golden hamster by BK virus, a human papovavirus.

Authors:  S Uchida; S Watanabe; T Aizawa; K Kato; A Furuno
Journal:  Gan       Date:  1976-12

7.  Mouse globin gene expression in erythroid and non-erythroid tissues.

Authors:  S Humphries; J Windass; R Williamson
Journal:  Cell       Date:  1976-02       Impact factor: 41.582
  7 in total
  2 in total

1.  Evolutionary conservation of the insulinoma gene rig and its possible function.

Authors:  C Inoue; K Shiga; S Takasawa; M Kitagawa; H Yamamoto; H Okamoto
Journal:  Proc Natl Acad Sci U S A       Date:  1987-10       Impact factor: 11.205

Review 2.  Regulation of proinsulin synthesis in pancreatic islets and a new aspect to insulin-dependent diabetes.

Authors:  H Okamoto
Journal:  Mol Cell Biochem       Date:  1981-06-09       Impact factor: 3.396
  2 in total

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