Literature DB >> 6245907

Inhibition of nitrosamine formation by ascorbic acid: participation of free radicals in its anaerobic reaction with nitrite.

W H Kalus, W G Filby.   

Abstract

The participation of semiquinone free radicals during the reaction of ascorbic acid with acidified sodium nitrite has been demonstrated by ESR spectroscopy unambiguously for the first time. Scavenging of the nitrosating agent, reflected by the observed free radical concentration, unexpectedly occurs with scarcely varying efficiency over the pH range 0.1--4.5.

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Year:  1980        PMID： 6245907     DOI： 10.1007/bf01953698

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  12 in total

1.  Kinetics of dimethylamine nitrosation in relation to nitrosamine carcinogenesis.

Authors:  S S Mirvish
Journal:  J Natl Cancer Inst       Date:  1970-03       Impact factor: 13.506

2.  Possible cocarcinogenic effects of coffee constituents.

Authors:  B C Challis; C D Bartlett
Journal:  Nature       Date:  1975-04-10       Impact factor: 49.962

3.  Phenolic antioxidants and the inhibition of hepatotoxicity from N-dimethylnitrosamine formed in situ in the rat stomach.

Authors:  B D Astill; L T Mulligan
Journal:  Food Cosmet Toxicol       Date:  1977-06

4.  Rapid nitrosation of phenols and its implications for health hazards from dietary nitrites.

Authors:  B C Challis
Journal:  Nature       Date:  1973-08-17       Impact factor: 49.962

5.  The electron spin resonance spectra of radical intermediates in the oxidation of ascorbic acid and related substances.

Authors:  G P Laroff; R W Fessenden; R H Schuler
Journal:  J Am Chem Soc       Date:  1972-12-27       Impact factor: 15.419

6.  Kinetics of the nitrosation of aminopyrine to give dimethylnitrosamine.

Authors:  S S Mirvish; B Gold; M Eagen; S Arnold
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1974

7.  Brief communication: ascorbic acid blocking of aminopyrine nitrosation in NZO-B1 mice.

Authors:  M Greenblatt
Journal:  J Natl Cancer Inst       Date:  1973-04       Impact factor: 13.506

8.  Nitrosamines as environmental carcinogens.

Authors:  W Lijinsky; S S Epstein
Journal:  Nature       Date:  1970-01-03       Impact factor: 49.962

9.  Estimate of the volatile nitrosamine content of UK food.

Authors:  T A Gough; K S Webb; R F Coleman
Journal:  Nature       Date:  1978-03-09       Impact factor: 49.962

10.  N-Nitrosodiethanolamine in cosmetics, lotions and shampoos.

Authors:  T Y Fan; U Goff; L Song; D H Fine; G P Arsenault; K Biemann
Journal:  Food Cosmet Toxicol       Date:  1977-10
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  5 in total

1.  Dietary N-nitroso compounds and risk of colorectal cancer: a case-control study in Newfoundland and Labrador and Ontario, Canada.

Authors:  Yun Zhu; Peizhon Peter Wang; Jing Zhao; Roger Green; Zhuoyu Sun; Barbara Roebothan; Josh Squires; Sharon Buehler; Elizabeth Dicks; Jinhui Zhao; Michelle Cotterchio; Peter T Campbell; Meera Jain; Patrick S Parfrey; John R Mclaughlin
Journal:  Br J Nutr       Date:  2013-10-25       Impact factor: 3.718

2.  Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis.

Authors:  B N Ames; R Cathcart; E Schwiers; P Hochstein
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

3.  Association between dietary nitrate and nitrite intake and sitespecific cancer risk: evidence from observational studies.

Authors:  Li Xie; Miao Mo; Hui-Xun Jia; Fei Liang; Jing Yuan; Ji Zhu
Journal:  Oncotarget       Date:  2016-08-30

Review 4.  Dietary Factors Modulating Colorectal Carcinogenesis.

Authors:  Filippo Vernia; Salvatore Longo; Gianpiero Stefanelli; Angelo Viscido; Giovanni Latella
Journal:  Nutrients       Date:  2021-01-03       Impact factor: 5.717

5.  Association Between Dietary Nitrite intake and Glioma Risk: A Systematic Review and Dose-Response Meta-Analysis of Observational Studies.

Authors:  Weichunbai Zhang; Jing Jiang; Yongqi He; Xinyi Li; Shuo Yin; Feng Chen; Wenbin Li
Journal:  Front Oncol       Date:  2022-07-08       Impact factor: 5.738
  5 in total

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