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Literature DB >> 624499

Effect of glucocorticoids on gastrin secretion in man.

S Seino, Y Seino, S Matsukura, H Kurahachi, M Ikeda, M Yawata, H Imura.

Abstract

In order to investigate the effect of glucocorticoids on gastrin secretion, plasma gastrin levels were measured by radioimmunoassay in patients with Cushing's syndrome and those treated with glucocorticoids. Fasting plasma gastrin levels were significantly higher in these patients than in normal subjects, with exaggerated response to food. Conversely, short-term treatment or intravenous infusion of glucocorticoids had no significant influence on gastrin secretion in normal subjects. The possible mechanism by which glucocorticoids cause hypergastrinaemia are discussed.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1978 PMID： 624499 PMCID： PMC1411767 DOI： 10.1136/gut.19.1.10

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

16 in total

1. Role of gastric secretions in activation of peptic ulcers by corticotropin (ACTH).

Authors: B I HIRSCHOWITZ; D H STREETEN; H M POLLARD; H A BOLDT
Journal: J Am Med Assoc Date: 1955-05-07

2. Major undesirable side-effects resulting from prednisolone and prednisone.

Authors: A J BOLLET; R BLACK; J J BUNIM
Journal: J Am Med Assoc Date: 1955-06-11

3. The incidence of peptic ulcer among patients on long term prednisone therapy.

Authors: L E MELTZER; A A BOCKMAN; W KANENSON; A COHEN
Journal: Gastroenterology Date: 1958-10 Impact factor: 22.682

4. Stress and duodenal ulcer.

Authors: L R DRAGSTEDT; L R DRAGSTEDT; S O EVANS; H RAGINS
Journal: Ann Surg Date: 1956-09 Impact factor: 12.969

5. Effect of adrenocorticotrophic hormone upon the gastric secretion of hydrochloric acid, pepsin and electrolytes in the dog.

Authors: R VILLARREAL; W F GANONG; S J GRAY
Journal: Am J Physiol Date: 1955-12

3. Duodenal G- and D-cell changes following corticosteroid administration. Immunocytochemical long-term study in guinea pigs.

Authors: E Xynos; J Vassilakis; K Aroni; C Kittas
Journal: Klin Wochenschr Date: 1987-02-02

4. Endocrinology of duodenal ulcer.

Authors: W Creutzfeldt; R Arnold
Journal: World J Surg Date: 1979-09-20 Impact factor: 3.352

4 in total

Effect of glucocorticoids on gastrin secretion in man.

1. Role of gastric secretions in activation of peptic ulcers by corticotropin (ACTH).

2. Major undesirable side-effects resulting from prednisolone and prednisone.

3. The incidence of peptic ulcer among patients on long term prednisone therapy.

4. Stress and duodenal ulcer.

5. Effect of adrenocorticotrophic hormone upon the gastric secretion of hydrochloric acid, pepsin and electrolytes in the dog.

6. Plasma gastrin responses to arginine in chronic pancreatitis.

7. Radioimmunoassay of gastrin. Fasting serum levels in humans with normal and high gastric acid secreation.

8. Influence of glucocorticoids on glucagon secretion and plasma amino acid concentrations in man.

9. Hypergastrinemia in hyperthyroidism.

10. Hypergastrinemia induced by glucocorticoid and corticotropin treatment in man.

1. Gut hormones in tropical malabsorption.

Review 2. Review of the toxicology of beclomethasone dipropionate.

3. Duodenal G- and D-cell changes following corticosteroid administration. Immunocytochemical long-term study in guinea pigs.

4. Endocrinology of duodenal ulcer.