Literature DB >> 519400

Gut hormones in tropical malabsorption.

H S Besterman, G C Cook, D L Sarson, N D Christofides, M G Bryant, M Gregor, S R Bloom.   

Abstract

Concentrations of various gut hormones were measured after a test breakfast in eight patients with severe tropical malabsorption and 12 controls. The patients with tropical malabsorption had greatly raised basal plasma motilin and enteroglucagon concentrations, but their postprandial release of both gastric inhibitory polypeptide and insulin was significantly reduced. The pattern of gut hormone release differed from that found in coeliac disease. The measurement of gut hormones, each of which has a specific site and function, thus throws new light on the pathophysiology of tropical malabsorption and may suggest approaches of treatment.

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Year:  1979        PMID： 519400      PMCID： PMC1596913          DOI： 10.1136/bmj.2.6200.1252

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  21 in total

1.  Current problems in the measurement of gastrin release. A reproducible measure of physiological gastrin release.

Authors:  R C Russel; S R Bloom; L P Fielding; M G Bryant
Journal:  Postgrad Med J       Date:  1976-10       Impact factor: 2.401

2.  Plasma enteroglucagon after jejunoileal bypass with 3:1 or 1:3 jejunoileal ratio.

Authors:  J J Holst; T I Sørensen; A N Andersen; F Stadil; B Andersen; K B Lauritsen; H C Klein
Journal:  Scand J Gastroenterol       Date:  1979       Impact factor: 2.423

3.  Inhibition of pancreas and gallbladder by pancreatic polypeptide.

Authors:  G R Greenberg; R F McCloy; T E Adrian; V S Chadwick; J H Baron; S R Bloom
Journal:  Lancet       Date:  1978-12-16       Impact factor: 79.321

4.  Gut-hormone profile in coeliac disease.

Authors:  H S Besterman; S R Bloom; D L Sarson; A M Blackburn; D I Johnston; H R Patel; J S Stewart; R Modigliani; S Guerin; C N Mallinson
Journal:  Lancet       Date:  1978-04-15       Impact factor: 79.321

5.  Distribution and release of human pancreatic polypeptide.

Authors:  T E Adrian; S R Bloom; M G Bryant; J M Polak; P H Heitz; A J Barnes
Journal:  Gut       Date:  1976-12       Impact factor: 23.059

6.  Effect of glucocorticoids on gastrin secretion in man.

Authors:  S Seino; Y Seino; S Matsukura; H Kurahachi; M Ikeda; M Yawata; H Imura
Journal:  Gut       Date:  1978-01       Impact factor: 23.059

7.  Effect of motilin on the rate of gastric emptying and gut hormone release during breakfast.

Authors:  N D Christofides; I M Modlin; M L Fitzpatrick; S R Bloom
Journal:  Gastroenterology       Date:  1979-05       Impact factor: 22.682

8.  Glucagon levels in normal and diabetic subjects: use of a specific immunoabsorbent for glucagon radioimmunoassay.

Authors:  F P Alford; S R Bloodm; J D Nabarro
Journal:  Diabetologia       Date:  1977-01       Impact factor: 10.122

9.  Intestinal adaptation after jejunoileal bypass in man.

Authors:  R E Barry; J Barisch; G A Bray; M A Sperling; R J Morin; J Benfield
Journal:  Am J Clin Nutr       Date:  1977-01       Impact factor: 7.045

10.  Tropical sprue: implications of Manson's concept.

Authors:  G C Cook
Journal:  J R Coll Physicians Lond       Date:  1978-07
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  23 in total

Review 1.  Gastrointestinal hormones regulating appetite.

Authors:  Owais Chaudhri; Caroline Small; Steve Bloom
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-07-29       Impact factor: 6.237

2.  Differential responses of the incretin hormones GIP and GLP-1 to increasing doses of dietary carbohydrate but not dietary protein in lean rats.

Authors:  Stephanie M Yoder; Qing Yang; Tammy L Kindel; Patrick Tso
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-06-03       Impact factor: 4.052

3.  Gut hormones in gastrointestinal disease.

Authors:  H S Besterman
Journal:  J Clin Pathol Suppl (Assoc Clin Pathol)       Date:  1978

Review 4.  Tropical sprue--its aetiology and pathogenesis.

Authors:  J Glynn
Journal:  J R Soc Med       Date:  1986-10       Impact factor: 5.344

Review 5.  Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease.

Authors:  A Zarrinpar; R Loomba
Journal:  Aliment Pharmacol Ther       Date:  2012-10-11       Impact factor: 8.171

6.  Pectin and complications after gastric surgery: normalisation of postprandial glucose and endocrine responses.

Authors:  D J Jenkins; S R Bloom; R H Albuquerque; A R Leeds; D L Sarson; G L Metz; K G Alberti
Journal:  Gut       Date:  1980-07       Impact factor: 23.059

Review 7.  The role of incretins in glucose homeostasis and diabetes treatment.

Authors:  Wook Kim; Josephine M Egan
Journal:  Pharmacol Rev       Date:  2008-12-12       Impact factor: 25.468

8.  Positive correlation between symptoms and circulating motilin, pancreatic polypeptide and gastrin concentrations in functional bowel disorders.

Authors:  D M Preston; T E Adrian; N D Christofides; J E Lennard-Jones; S R Bloom
Journal:  Gut       Date:  1985-10       Impact factor: 23.059

9.  Molecular mechanisms underlying nutrient detection by incretin-secreting cells.

Authors:  Frank Reimann
Journal:  Int Dairy J       Date:  2010-04       Impact factor: 3.032

10.  Gastrointestinal regulatory peptide storage granule abnormalities in jejunal mucosal diseases.

Authors:  J Dawson; M G Bryant; S R Bloom; T J Peters
Journal:  Gut       Date:  1984-06       Impact factor: 23.059
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