Literature DB >> 6244947

The interaction of bovine pancreatic deoxyribonuclease I and skeletal muscle actin.

H G Mannherz, R S Goody, M Konrad, E Nowak.   

Abstract

The rate of exchange of actin-bound nucleotide is decreased by a factor of about 20 when actin is complexed with DNAase I without affecting the binding constant of calcium for actin. Binding constants of DNAase I to monomeric and filamentous actin were determined to be 5 X 10(8) M-1 and 1.2 X 10(4) M-1 respectively. The depolymerisation of F-actin by DNAase I appears to be due to a shift in the G-F equilibrium of actin by DNAase I. Inhibition of the DNA-degrading activity of DNAase I by G-actin is of the partially competitive type.

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Year:  1980        PMID: 6244947     DOI: 10.1111/j.1432-1033.1980.tb04437.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN: 0014-2956


  45 in total

1.  The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.

Authors:  P J Goldschmidt-Clermont; M I Furman; D Wachsstock; D Safer; V T Nachmias; T D Pollard
Journal:  Mol Biol Cell       Date:  1992-09       Impact factor: 4.138

2.  Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy.

Authors:  Mirco Müller; Antonina Joanna Mazur; Elmar Behrmann; Ralph P Diensthuber; Michael B Radke; Zheng Qu; Christoph Littwitz; Stefan Raunser; Cora-Ann Schoenenberger; Dietmar J Manstein; Hans Georg Mannherz
Journal:  Cell Mol Life Sci       Date:  2012-05-29       Impact factor: 9.261

3.  Coarse-grained models for simulations of multiprotein complexes: application to ubiquitin binding.

Authors:  Young C Kim; Gerhard Hummer
Journal:  J Mol Biol       Date:  2007-11-28       Impact factor: 5.469

4.  Disruption of microfilament organization in living nonmuscle cells by microinjection of plasma vitamin D-binding protein or DNase I.

Authors:  J M Sanger; G Dabiri; B Mittal; M A Kowalski; J G Haddad; J W Sanger
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

5.  Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition.

Authors:  C Kayalar; T Ord; M P Testa; L T Zhong; D E Bredesen
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-05       Impact factor: 11.205

6.  Mapping the binding site of thymosin beta4 on actin by competition with G-actin binding proteins indicates negative co-operativity between binding sites located on opposite subdomains of actin.

Authors:  E Ballweber; E Hannappel; T Huff; H G Mannherz
Journal:  Biochem J       Date:  1997-11-01       Impact factor: 3.857

7.  Poster Viewing Sessions PB01-B01 to PB03-V09.

Authors: 
Journal:  J Cereb Blood Flow Metab       Date:  2019-07       Impact factor: 6.200

8.  Enzymological characterization of the nuclease domain from the bacterial toxin colicin E9 from Escherichia coli.

Authors:  A J Pommer; R Wallis; G R Moore; R James; C Kleanthous
Journal:  Biochem J       Date:  1998-09-01       Impact factor: 3.857

9.  Characterization of a pancreatic DNase from pyloric caeca of atlantic cod (Gadus morhua L.).

Authors:  K O Strætkvern; A J Raae; B T Walther
Journal:  Fish Physiol Biochem       Date:  1992-02       Impact factor: 2.794

10.  The inhibition of bovine and rat parotid deoxyribonuclease I by skeletal muscle actin. A biochemical and immunocytochemical study.

Authors:  H G Mannherz; V Kreuder; J Koch; J Dieckhoff; D Drenckhahn
Journal:  Biochem J       Date:  1982-11-01       Impact factor: 3.857

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