Literature DB >> 6244916

Comparative in vitro activity of cefotaxime (HR 756).

G Peters, G Pulverer.   

Abstract

The in vitro activity of cefotaxime (HR 756) was tested in comparison with cefuroxime, cefamondole, cefoxitin, cefazolin, ampicillin, mezlocilline, gentamicin and amicacin. MIC values were investigated on 168 freshly isolated gram-positive and gram-negative bacteria from clinical sources. Enterococci and Pseudomonas aeruginosa behaved cefotaxime-resistant. All the other species examined showed a very good sensitivity range against cefotaxime. Cefotaxime was the most active antibiotic of our study.

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Year:  1980        PMID： 6244916     DOI： 10.1159/000237902

Source DB:  PubMed          Journal:  Chemotherapy        ISSN： 0009-3157            Impact factor:   2.544


  5 in total

1.  The human pharmacokinetics of cefotaxime and its metabolites and the role of renal tubular secretion on their elimination.

Authors:  R M Ings; D S Reeves; L O White; R P Bax; M J Bywater; H A Holt
Journal:  J Pharmacokinet Biopharm       Date:  1985-04

2.  Clinical experience with cefotaxime for the therapy of bacteremias due to gram-positive organisms.

Authors:  C J Schleupner
Journal:  Infection       Date:  1985       Impact factor: 3.553

3.  Clinical experience of cefotaxime in infections caused by gram-positive pathogens.

Authors:  D Bassetti; M Solbiati; G Fraizzoli
Journal:  Infection       Date:  1985       Impact factor: 3.553

4.  Cefotaxime and desacetylcefotaxime pharmacokinetics in infants and children with meningitis.

Authors:  J M Trang; R F Jacobs; G L Kearns; A L Brown; T G Wells; F L Underwood; R B Kluza
Journal:  Antimicrob Agents Chemother       Date:  1985-12       Impact factor: 5.191

5.  In vitro studies with cefotaxime: disk diffusion susceptibility tests.

Authors:  S Shadomy; E L Chan
Journal:  J Clin Microbiol       Date:  1982-08       Impact factor: 5.948
  5 in total

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