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Literature DB >> 6237903

The activity of ciprofloxacin and other 4-quinolones against Chlamydia trachomatis and Mycoplasmas in vitro.

G L Ridgway, G Mumtaz, F G Gabriel, J D Oriel.

Abstract

Ciprofloxacin was found to be the most active of a group of 4-quinolone antibiotics tested against the SA2f strain of Chlamydia trachomatis (MBC and MIC 1.0 mg/l). Against genital isolates of Chlamydia trachomatis, ciprofloxacin was twice as active as rosoxacin. Ciprofloxacin showed similar activity to that of oxytetracycline against clinical isolates of Mycoplasma hominis and Ureaplasma urealyticum, and was 8-fold more active than rosoxacin against the latter.

Entities: Chemical Disease Species

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Year: 1984 PMID： 6237903 DOI： 10.1007/bf01977491

Source DB: PubMed Journal: Eur J Clin Microbiol ISSN： 0722-2211 Impact factor: 3.267

7 in total

1. A method for testing the antibiotic susceptibility of Chlamydia trachomatis in a cell culture system.

Authors: G L Ridgway; J M Owen; J D Oriel
Journal: J Antimicrob Chemother Date: 1976-03 Impact factor: 5.790

2. Pharmacokinetics and tissue penetration of ciprofloxacin.

Authors: B Crump; R Wise; J Dent
Journal: Antimicrob Agents Chemother Date: 1983-11 Impact factor: 5.191

3. In vitro activity of norfloxacin against Chlamydia trachomatis.

Authors: H Meier-Ewert; G Weil; G Millott
Journal: Eur J Clin Microbiol Date: 1983-06 Impact factor: 3.267

4. The incidence of tetracycline-resistant strains of Ureaplasma urealyticum.

Authors: R T Evans; D Taylor-Robinson
Journal: J Antimicrob Chemother Date: 1978-01 Impact factor: 5.790

5. Mycoplasmas of various hosts and their antibiotic sensitivities.

Authors: D Taylor-Robinson
Journal: Postgrad Med J Date: 1967-03 Impact factor: 2.401

6. Pharmacokinetics of norfloxacin in healthy volunteers and patients with renal and hepatic damage.

Authors: M Eandi; I Viano; F Di Nola; L Leone; E Genazzani
Journal: Eur J Clin Microbiol Date: 1983-06 Impact factor: 3.267

7. The antimicrobial susceptibility of Chlamydia trachomatis in cell culture.

Authors: G L Ridgway; J M Owen; J D Oriel
Journal: Br J Vener Dis Date: 1978-04

7 in total

33 in total

1. Peritonitis due to Mycoplasma hominis and Ureaplasma urealyticum in a liver transplant recipient.

Authors: M Haller; H Forst; G Ruckdeschel; H Denecke; K Peter
Journal: Eur J Clin Microbiol Infect Dis Date: 1991-03 Impact factor: 3.267

2. Near fatal puerperal fever due to Mycoplasma hominis.

Authors: M J Young; R A Cox
Journal: Postgrad Med J Date: 1990-02 Impact factor: 2.401

3. In vitro activity of the two new 4-quinolones A56619 and A56620 against Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum and Gardnerella vaginalis.

Authors: K H Tjiam; J H Wagenvoort; B van Klingeren; P Piot; E Stolz; M F Michel
Journal: Eur J Clin Microbiol Date: 1986-10 Impact factor: 3.267

10. In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391.

Authors: K B Waites; L B Duffy; T Schmid; D Crabb; M S Pate; G H Cassell
Journal: Antimicrob Agents Chemother Date: 1991-06 Impact factor: 5.191

The activity of ciprofloxacin and other 4-quinolones against Chlamydia trachomatis and Mycoplasmas in vitro.

1. A method for testing the antibiotic susceptibility of Chlamydia trachomatis in a cell culture system.

2. Pharmacokinetics and tissue penetration of ciprofloxacin.

3. In vitro activity of norfloxacin against Chlamydia trachomatis.

4. The incidence of tetracycline-resistant strains of Ureaplasma urealyticum.

5. Mycoplasmas of various hosts and their antibiotic sensitivities.

6. Pharmacokinetics of norfloxacin in healthy volunteers and patients with renal and hepatic damage.

7. The antimicrobial susceptibility of Chlamydia trachomatis in cell culture.

1. Peritonitis due to Mycoplasma hominis and Ureaplasma urealyticum in a liver transplant recipient.

2. Near fatal puerperal fever due to Mycoplasma hominis.

3. In vitro activity of the two new 4-quinolones A56619 and A56620 against Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum and Gardnerella vaginalis.

4. Effect of renal impairment on distribution of ofloxacin.

5. Susceptibilities of genital mycoplasmas to the newer quinolones as determined by the agar dilution method.

6. In vitro activity and mode of action of fluoroquinolones.

Review 7. Antimicrobial chemotherapy of chlamydial infection: where next?

8. Clinical efficacy of ciprofloxacin versus doxycycline in the treatment of non-gonococcal urethritis in males.

9. Failure of norfloxacin to eradicate Chlamydia trachomatis in nongonococcal urethritis.

10. In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391.