Literature DB >> 3438148

In vitro activity and mode of action of fluoroquinolones.

L Verbist1.   

Abstract

The in vitro activity of nine fluoroquinolones has been determined by agar dilution method against 1100 clinical isolates of different microorganisms: 412 Enterobacteriaceae, 93 non-fermenters, 398 enteropathogens, 140 Gram-positive cocci, 31 Haemophilus and 26 gonococci. The bactericidal activity tested in broth against different representative isolates was generally similar to the inhibitory concentration. Killing kinetics studied in different isolates of Enterobacteriaceae, in Pseudomonas aeruginosa, Vibrio cholerae, Staphylococcus aureus and Streptococcus faecalis showed a very rapid bactericidal effect, after 2 to 8 h of contact, in all species except in Streptococcus faecalis.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3438148     DOI： 10.1007/BF02075251

Source DB:  PubMed          Journal:  Pharm Weekbl Sci        ISSN： 0167-6555


  23 in total

1.  In-vitro sensitivity of legionellas, meningococci and mycoplasmas to ciprofloxacin and enoxacin.

Authors:  R J Fallon; W M Brown
Journal:  J Antimicrob Chemother       Date:  1985-06       Impact factor: 5.790

2.  Treatment of chronic salmonella carriers with ciprofloxacin.

Authors:  G Diridl; H Pichler; D Wolf
Journal:  Eur J Clin Microbiol       Date:  1986-04       Impact factor: 3.267

3.  Activity of quinolones against Legionellaceae.

Authors:  D J Pohlod; L D Saravolatz
Journal:  J Antimicrob Chemother       Date:  1986-04       Impact factor: 5.790

4.  Norfloxacin versus thiamphenicol for treatment of uncomplicated gonorrhea in Rwanda.

Authors:  J Bogaerts; W Martinez Tello; L Verbist; P Piot; J Vandepitte
Journal:  Antimicrob Agents Chemother       Date:  1987-03       Impact factor: 5.191

5.  Comparison of norfloxacin and nalidixic acid for treatment of dysentery caused by Shigella dysenteriae type 1 in adults.

Authors:  F Rogerie; D Ott; J Vandepitte; L Verbist; P Lemmens; I Habiyaremye
Journal:  Antimicrob Agents Chemother       Date:  1986-05       Impact factor: 5.191

Review 6.  The mode of action of 4-quinolones and possible mechanisms of resistance.

Authors:  J T Smith
Journal:  J Antimicrob Chemother       Date:  1986-11       Impact factor: 5.790

7.  Quinolones in the treatment of gonorrhoea and Chlamydia trachomatis infections.

Authors:  E Stolz; M J Tegelberg-Stassen; A H Van der Willigen; J C Van der Hoek; T Van Joost; L Mooi; J H Wagenvoort
Journal:  Pharm Weekbl Sci       Date:  1986-02-21

8.  Single dose ciprofloxacin for treating gonococcal infections in men.

Authors:  P S Loo; G L Ridgway; J D Oriel
Journal:  Genitourin Med       Date:  1985-10

9.  Ciprofloxacin for selective decontamination of the alimentary tract in patients with acute leukemia during remission induction treatment: the effect on fecal flora.

Authors:  M Rozenberg-Arska; A W Dekker; J Verhoef
Journal:  J Infect Dis       Date:  1985-07       Impact factor: 5.226

10.  The antimicrobial activity of ciprofloxacin against Legionella species and the treatment of experimental Legionella pneumonia in guinea pigs.

Authors:  A Saito; H Koga; H Shigeno; K Watanabe; K Mori; S Kohno; Y Shigeno; Y Suzuyama; K Yamaguchi; M Hirota
Journal:  J Antimicrob Chemother       Date:  1986-08       Impact factor: 5.790
View more
  2 in total

Review 1.  Ofloxacin. A reappraisal of its antimicrobial activity, pharmacology and therapeutic use.

Authors:  P A Todd; D Faulds
Journal:  Drugs       Date:  1991-11       Impact factor: 9.546

Review 2.  Fluoroquinolones: use of clinical data to aid formulary choice by the system of objective judgement analysis (SOJA) method.

Authors:  R Janknegt
Journal:  Pharmacoeconomics       Date:  1994-07       Impact factor: 4.981
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.