| Literature DB >> 6237064 |
T J Savelkoul, S J Oldenburg, W J Van Oort, S A Duursma.
Abstract
The labeling of methylene diphosphonate with 99mTc is possible after reduction of pertechnetate by means of controlled potential electrolysis. This results in a [99mTc]MDP complex which differs slightly from 99mTc(Sn)-MDP in paper and gel chromatography. The scintigraphic images of both preparations are comparable in quality. Biodistribution in rats shows a higher bone uptake for the 99mTc(Sn)-MDP complex, whereas [99mTc]MDP shows a higher uptake in the gastric wall.Entities:
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Year: 1984 PMID： 6237064 DOI： 10.1016/0020-708x(84)90076-0
Source DB: PubMed Journal: Int J Appl Radiat Isot ISSN： 0020-708X