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Literature DB >> 6235177

Phylogeny of interleukins: growth factors produced by leucocytes of the cyprinid fish, Cyprinus carpio L.

Abstract

Supernatants of phytohaemagglutinin (PHA)-activated pronephric leucocytes from carp (Cyprinus carpio L.) contain a lymphocyte growth factor which can induce a proliferative response of purified lymphoblasts but not freshly isolated leucocytes. The growth-promoting activity can be reduced by absorbing the supernatant with mitogen-activated blasts. In addition, increased incorporation of tritiated thymidine into PHA-activated blast cells is also induced by supernatants from two-way mixed leucocyte cultures. The data show that even at the evolutionary level of teleost fish, amplifying/regulatory leucocyte products exist. It is suggested that these factors play as important a role in the regulation of the immune response in fish as they do in mammals.

Entities: Chemical Species

Mesh：

Substances：

Year: 1984 PMID： 6235177 PMCID： PMC1454478

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

15 in total

1. T-cell growth factor-mediated T-cell proliferation.

Authors: K A Smith; S Gillis; P E Baker; D McKenzie; F W Ruscetti
Journal: Ann N Y Acad Sci Date: 1979 Impact factor: 5.691

2. T cell growth factor: parameters of production and a quantitative microassay for activity.

Authors: S Gillis; M M Ferm; W Ou; K A Smith
Journal: J Immunol Date: 1978-06 Impact factor: 5.422

3. Macrophage-independent activation of helper T cells. I. Production of Interleukin 2.

Authors: J J Farrar; S B Mizel; J Fuller-Farrar; W L Farrar; M L Hilfiker
Journal: J Immunol Date: 1980-08 Impact factor: 5.422

4. T-T cell interactions during in vitro cytotoxic T lymphocyte (CTL) responses. II. Helper factor from activated Lyt 1+ T cells is rate limiting i) in T cell responses to nonimmunogenic alloantigen, ii) in thymocyte responses to allogeneic stimulator cells, and III) recruits allo- or H-2-restricted CTL precursors from the Lyt 123+ T subset.

Authors: H Wagner; M Räollinghoff; K Pfizenmaier; C Hardt; G Johnscher
Journal: J Immunol Date: 1980-03 Impact factor: 5.422

Review 5. Role of lymphokine and antigen in the control of specific T cell responses.

Authors: K J Lafferty; L Andrus; S J Prowse
Journal: Immunol Rev Date: 1980 Impact factor: 12.988

6. A simplified method for the production of murine T-cell growth factor free of lectin.

Authors: P J Spiess; S A Rosenberg
Journal: J Immunol Methods Date: 1981 Impact factor: 2.303

7. Biochemical characterization of lymphocyte regulatory molecules. II. Purification of a class of rat and human lymphokines.

Authors: S Gillis; K A Smith; J Watson
Journal: J Immunol Date: 1980-04 Impact factor: 5.422

8. Effects of costimulator on immune responses in vitro.

Authors: J Shaw; V Monticone; G Mills; V Paetkau
Journal: J Immunol Date: 1978-06 Impact factor: 5.422

9. The role of interleukin-2 (IL-2) in the differentiatin of cytotoxic T cells: the effect of monoclonal anti-IL-2 antibody and absorption with IL-2 dependent T cell lines.

Authors: D E Kern; S Gillis; M Okada; C S Henney
Journal: J Immunol Date: 1981-10 Impact factor: 5.422

3. Characterisation and expression analysis of interleukin 2 (IL-2) and IL-21 homologues in the Japanese pufferfish, Fugu rubripes, following their discovery by synteny.

Authors: Steve Bird; Jun Zou; Tomoya Kono; Masahiro Sakai; Johannes Martinus Dijkstra; Chris Secombes
Journal: Immunogenetics Date: 2004-12-11 Impact factor: 2.846

3 in total