Literature DB >> 6226461

Is there a predisposition for meiotic nondisjunction that may be detected by mitotic hyperploidy?

C Staessen, A M Maes, M Kirsch-Volders, C Susanne.   

Abstract

The aneuploidy frequencies have been studied in vitro in lymphocytes from couples with recurrent abortions, from parents of a trisomic child and from control couples with at least two normal children; c-heterochromatin variants have been analysed on the same samples by length measurements. A significant increase of hyperploid cells has been observed in the lymphocytes from parents of a trisomic child and couples with recurrent abortions as well. However, no consistent correlation has been found so far between c-heterochromatin variants and an increase of aneuploidy.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6226461

Source DB:  PubMed          Journal:  Clin Genet        ISSN： 0009-9163            Impact factor:   4.438


  8 in total

1.  Replication asynchrony increases in women at risk for aneuploid offspring.

Authors:  A Amiel; O Reish; E Gaber; I Kedar; R Diukman; M Fejgin
Journal:  Chromosome Res       Date:  2000       Impact factor: 5.239

2.  The frequency of aneuploidy in cultured lymphocytes is correlated with age and gender but not with reproductive history.

Authors:  G P Nowinski; D L Van Dyke; B C Tilley; G Jacobsen; V R Babu; M J Worsham; G N Wilson; L Weiss
Journal:  Am J Hum Genet       Date:  1990-06       Impact factor: 11.025

3.  Increased spindle resistance to antimicrotubule agents in cells prone to chromosomal nondisjunction.

Authors:  L Avivi; A Dotan; Y Ravia; A Amiel; H Shacham; Y Neumann
Journal:  Hum Genet       Date:  1989-09       Impact factor: 4.132

4.  Spindle microtubular dysfunction in mothers of Down syndrome children.

Authors:  J H Ford
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

5.  Differences in the error mechanisms affecting sex and autosomal chromosomes in women of different ages within the reproductive age group.

Authors:  J H Ford; J A Russell
Journal:  Am J Hum Genet       Date:  1985-09       Impact factor: 11.025

Review 6.  Role of Trisomy 21 Mosaicism in Sporadic and Familial Alzheimer's Disease.

Authors:  Huntington Potter; Antoneta Granic; Julbert Caneus
Journal:  Curr Alzheimer Res       Date:  2016       Impact factor: 3.498

7.  Evidence for the repeated primary non-disjunction of chromosome 21 as a result of premature centromere division (PCD).

Authors:  P H Fitzgerald; S A Archer; C M Morris
Journal:  Hum Genet       Date:  1986-01       Impact factor: 4.132

8.  Increased spindle resistance to antimicrotubule agents in women of high risk for meiotic nondisjunction.

Authors:  A Dotan; L Avivi
Journal:  Hum Genet       Date:  1986-07       Impact factor: 4.132
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.