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Literature DB >> 6221840

The distribution and possible significance of cells identified in human lymphoid tissue by the monoclonal antibody HNK-1.

Abstract

The monoclonal antibody HNK-1 identifies a subpopulation of lymphocytes containing almost all of the natural killer (NK) and antibody-dependent killer (K) cell activity. Using an immunoperoxidase technique on frozen tissue sections of human spleen, tonsil and lymph node we have demonstrated that cells identified by this antibody are almost exclusively confined to germinal centres. Comparison with the distribution of B cells, T cells and T cell subsets underlines the distinctive distribution of these cells for which a physiological role in the maturation of antibody affinity during immune responses is suggested.

Entities: Gene Species

Mesh：

Substances：
Antibodies, Monoclonal

Year: 1983 PMID： 6221840 PMCID： PMC1536772

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

15 in total

1. Memory B cells at successive stages of differentiation: expression of surface IgD and capacity for self renewal.

Authors: S J Black; T Tokushia; L A Herzenberg; L A Herzenberg
Journal: Eur J Immunol Date: 1980-11 Impact factor: 5.532

2. A differentiation antigen of human NK and K cells identified by a monoclonal antibody (HNK-1).

Authors: T Abo; C M Balch
Journal: J Immunol Date: 1981-09 Impact factor: 5.422

3. The cellular basis of immunological recovery in nude mice after thymus grafting.

Authors: M De Sousa; H Pritchard
Journal: Immunology Date: 1974-04 Impact factor: 7.397

4. Isolation of human NK cells by density gradient centrifugation.

Authors: T Timonen; E Saksela
Journal: J Immunol Methods Date: 1980 Impact factor: 2.303

5. The nature of piecemeal necrosis in chronic active hepatitis.

Authors: J F Kerr; W G Cooksley; J Searle; J W Halliday; W J Halliday; L Holder; I Roberts; W Burnett; L W Powell
Journal: Lancet Date: 1979-10-20 Impact factor: 79.321

6. Immunohistologic analysis of the organization of normal lymphoid tissue and non-Hodgkin's lymphomas.

Authors: H Stein; A Bonk; G Tolksdorf; K Lennert; H Rodt; J Gerdes
Journal: J Histochem Cytochem Date: 1980-08 Impact factor: 2.479

7. Multiple activities of a cloned cell line mediating natural killer cell function.

Authors: G Nabel; L R Bucalo; J Allard; H Wigzell; H Cantor
Journal: J Exp Med Date: 1981-06-01 Impact factor: 14.307

8. Memory B cells at successive stages of differentiation. Affinity maturation and the role of IgD receptors.

Authors: L A Herzenberg; S J Black; T Tokuhisa; L A Herzenberg
Journal: J Exp Med Date: 1980-05-01 Impact factor: 14.307

9. Distribution of T cell subsets in human lymph nodes.

Authors: S Poppema; A K Bhan; E L Reinherz; R T McCluskey; S F Schlossman
Journal: J Exp Med Date: 1981-01-01 Impact factor: 14.307

10. ELECTRON MICROSCOPE OBSERVATIONS ON TINGIBLE BODY MACROPHAGES IN MOUSE SPLEEN.

Authors: D C SWARTZENDRUBER; C C CONGDON
Journal: J Cell Biol Date: 1963-12 Impact factor: 10.539

21 in total

Review 1. Follicular helper T cells in immunity and systemic autoimmunity.

Authors: Joseph E Craft
Journal: Nat Rev Rheumatol Date: 2012-05-01 Impact factor: 20.543

Review 2. T cells that promote B-Cell maturation in systemic autoimmunity.

Authors: Jason S Weinstein; Sairy G Hernandez; Joe Craft
Journal: Immunol Rev Date: 2012-05 Impact factor: 12.988

3. Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses.

Authors: Hyung W Lim; Peter Hillsamer; Chang H Kim
Journal: J Clin Invest Date: 2004-12 Impact factor: 14.808

4. Tonsillar mapping of determinants found on normal lymphoreticular (T,B,K, immature and macrophage) and myeloblastic leukemia cells.

Authors: E M McMillan; L Stoneking; G B Humphrey; J Rapacz
Journal: Am J Pathol Date: 1987-03 Impact factor: 4.307

5. Heterogeneity of human natural killer cells in the spleen.

Authors: T Witte; K Wordelmann; R E Schmidt
Journal: Immunology Date: 1990-01 Impact factor: 7.397

6. Isolation and characterization of Leu 7+ germinal-center cells with the T helper-cell phenotype and granular lymphocyte morphology.

Authors: A Velardi; A B Tilden; R Millo; C E Grossi
Journal: J Clin Immunol Date: 1986-05 Impact factor: 8.317