Literature DB >> 6219630

Flushing in rosacea: a possible mechanism.

M Guarrera, A Parodi, C Cipriani, C Divano, A Rebora.   

Abstract

Flushing in rosacea has been investigated by means of (a) pharmacological inhibition of some possible chemical mediators and (b) titration of bradykinin as a possible effector directly in the blood. Clonidine-inhibited flushing was seen in all patients (mean 45%), other drugs had poorer results. Bradykinin increased in all patients at the climax of flushing (mean 60%). These findings support the hypothesis that epinephrine promotes a bradykinin release responsible for vasodilation.

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Year:  1982        PMID： 6219630     DOI： 10.1007/bf00509061

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  19 in total

1.  RELEASE OF A KININ PEPTIDE IN THE CARCINOID SYNDROME.

Authors:  J A OATES; K MELMON; A SJOERDSMA; L GILLESPIE; D T MASON
Journal:  Lancet       Date:  1964-03-07       Impact factor: 79.321

2.  [Stimulating effect of alcohol on adrenalin & noradrenalin metabolism in man].

Authors:  I ABELIN; C HERREN; W BERLI
Journal:  Helv Med Acta       Date:  1958-11

3.  The relationship between glandular activity, bradykinin formation and functional vasodilatation in the submandibular salivary gland.

Authors:  S M HILTON; G P LEWIS
Journal:  J Physiol       Date:  1956-11-28       Impact factor: 5.182

4.  Clonidine and facial flushing in rosacea.

Authors:  W J Cunliffe; B Dodman; J G Binner
Journal:  Br Med J       Date:  1977-01-08

5.  A unique syndrome associated with secretion of 5-hydroxytryptophan by metastatic gastric carcinoids.

Authors:  J A OATES; A SJOERDSMA
Journal:  Am J Med       Date:  1962-03       Impact factor: 4.965

6.  Menopausal flushing: double-blind trial of a non-hormonal medication.

Authors:  J R Clayden; J W Bell; P Pollard
Journal:  Br Med J       Date:  1974-03-09

7.  Letter: Effect of clonidine on nicotinic-acid flushing.

Authors:  K Sigroth
Journal:  Lancet       Date:  1974-07-06       Impact factor: 79.321

8.  Blood prostaglandin activity associated with noradrenaline-provoked flush in the carcinoid syndrome.

Authors:  A G Smith; M W Greaves
Journal:  Br J Dermatol       Date:  1974-05       Impact factor: 9.302

9.  Evidence for the release of bradykinin in carcinoid syndrome.

Authors:  J A Oates; W A Pettinger; R B Doctor
Journal:  J Clin Invest       Date:  1966-02       Impact factor: 14.808

10.  Formation of amines in the gastric mucosa of the rat.

Authors:  R Hakanson
Journal:  Nature       Date:  1965-11-20       Impact factor: 49.962
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  6 in total

1.  Neurovascular and neuroimmune aspects in the pathophysiology of rosacea.

Authors:  Verena D Schwab; Mathias Sulk; Stephan Seeliger; Pawel Nowak; Jerome Aubert; Christian Mess; Michel Rivier; Isabelle Carlavan; Patricia Rossio; Dieter Metze; Jörg Buddenkotte; Ferda Cevikbas; Johannes J Voegel; Martin Steinhoff
Journal:  J Investig Dermatol Symp Proc       Date:  2011-12

Review 2.  [Rosacea. Clinical features, pathogenesis and therapy].

Authors:  P Lehmann
Journal:  Hautarzt       Date:  2005-09       Impact factor: 0.751

3.  Alcohol intake and risk of rosacea in US women.

Authors:  Suyun Li; Eunyoung Cho; Aaron M Drucker; Abrar A Qureshi; Wen-Qing Li
Journal:  J Am Acad Dermatol       Date:  2017-04-20       Impact factor: 11.527

4.  Rosacea: disturbed defense against brain overheating.

Authors:  H Brinnel; J Friedel; M Caputa; M Cabanac; E Grosshans
Journal:  Arch Dermatol Res       Date:  1989       Impact factor: 3.017

5.  The Risk of Rosacea According to Chronic Diseases and Medications: A 5-Year Retrospective, Multi-Institutional Case-Control Study.

Authors:  Jee Hee Son; Bo Young Chung; Min Je Jung; Yong Won Choi; Hye One Kim; Chun Wook Park
Journal:  Ann Dermatol       Date:  2018-10-26       Impact factor: 1.444

6.  Assessment of Tachykinin Receptor 3' Gene Polymorphism rs3733631 in Rosacea.

Authors:  Anthony Karpouzis; Paschalis Avgeridis; Gregory Tripsianis; Elisavet Gatzidou; Niki Kourmouli; Stavroula Veletza
Journal:  Int Sch Res Notices       Date:  2015-09-30
  6 in total

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