Suyun Li1, Eunyoung Cho2, Aaron M Drucker3, Abrar A Qureshi2, Wen-Qing Li4. 1. Department of Epidemiology, School of Public Health, Shandong University, Jinan, Shandong Province, China. 2. Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, Rhode Island; Department of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. 3. Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, Rhode Island. 4. Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, Rhode Island; Department of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island. Electronic address: wen-qing_li@brown.edu.
Abstract
BACKGROUND: The epidemiologic association between alcohol and rosacea is unclear and inconsistent based on the previous cross-sectional or case-control studies. OBJECTIVE: We conducted a cohort study to determine the association between alcohol intake and the risk of rosacea in women. METHODS: A total of 82,737 women were included from the Nurses' Health Study II (1991-2005). Information on alcohol intake was collected every 4 years during follow-up. Information on history of clinician-diagnosed rosacea and year of diagnosis was collected in 2005. RESULTS: Over 14 years of follow-up, we identified 4945 cases of rosacea. Compared with never drinkers, increased alcohol intake was associated with a significantly increased risk of rosacea (Ptrend <.0001). The multivariate-adjusted hazard ratios (HRs) and confidence intervals (CIs) were 1.12 (95% CI 1.05-1.20) for alcohol intake of 1-4 g/day and 1.53 (1.26-1.84) for ≥30 g/day. The associations remained consistent across categories of smoking status. Further examination of types of alcoholic beverage consumed revealed that white wine (Ptrend <.0001) and liquor intake (Ptrend = .0006) were significantly associated with a higher risk of rosacea. LIMITATIONS: This was an epidemiologic study without examination into etiologic mechanisms. CONCLUSIONS: Alcohol intake was significantly associated with an increased risk of rosacea in women.
BACKGROUND: The epidemiologic association between alcohol and rosacea is unclear and inconsistent based on the previous cross-sectional or case-control studies. OBJECTIVE: We conducted a cohort study to determine the association between alcohol intake and the risk of rosacea in women. METHODS: A total of 82,737 women were included from the Nurses' Health Study II (1991-2005). Information on alcohol intake was collected every 4 years during follow-up. Information on history of clinician-diagnosed rosacea and year of diagnosis was collected in 2005. RESULTS: Over 14 years of follow-up, we identified 4945 cases of rosacea. Compared with never drinkers, increased alcohol intake was associated with a significantly increased risk of rosacea (Ptrend <.0001). The multivariate-adjusted hazard ratios (HRs) and confidence intervals (CIs) were 1.12 (95% CI 1.05-1.20) for alcohol intake of 1-4 g/day and 1.53 (1.26-1.84) for ≥30 g/day. The associations remained consistent across categories of smoking status. Further examination of types of alcoholic beverage consumed revealed that white wine (Ptrend <.0001) and liquor intake (Ptrend = .0006) were significantly associated with a higher risk of rosacea. LIMITATIONS: This was an epidemiologic study without examination into etiologic mechanisms. CONCLUSIONS:Alcohol intake was significantly associated with an increased risk of rosacea in women.
Authors: Ying Bao; Monica L Bertoia; Elizabeth B Lenart; Meir J Stampfer; Walter C Willett; Frank E Speizer; Jorge E Chavarro Journal: Am J Public Health Date: 2016-07-26 Impact factor: 9.308
Authors: Wen-Qing Li; Eunyoung Cho; Martin A Weinstock; Hasan Mashfiq; Abrar A Qureshi Journal: Am J Public Health Date: 2016-07-26 Impact factor: 9.308
Authors: J Tan; U Blume-Peytavi; J P Ortonne; K Wilhelm; L Marticou; E Baltas; M Rivier; L Petit; P Martel Journal: Br J Dermatol Date: 2013-09 Impact factor: 9.302
Authors: Suyun Li; Michael L Chen; Aaron M Drucker; Eunyoung Cho; Hao Geng; Abrar A Qureshi; Wen-Qing Li Journal: JAMA Dermatol Date: 2018-12-01 Impact factor: 10.282