Literature DB >> 6219285

Mutagenesis resulting from depurination is an SOS process.

R M Schaaper, B W Glickman, L A Loeb.   

Abstract

When bacteriophage phi X174 am3 DNA depurinated in vitro is transfected into E. coli spheroplasts prepared from bacteria previously exposed to UV light, a strong mutagenic response is observed. This mutagenic response does not occur in spheroplasts derived from pre-irradiated bacteria carrying defective recA, recF or umuC genes. These findings indicate that mutagenesis at apurinic sites is an SOS-dependent process. The mutagenic response is not dependent on the multiplicity of transfection. This suggests that mutagenesis is not mediated by recombination.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6219285     DOI： 10.1016/0027-5107(82)90186-5

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  22 in total

1.  Backbone Flexibility Influences Nucleotide Incorporation by Human Translesion DNA Polymerase η opposite Intrastrand Cross-Linked DNA.

Authors:  Derek K O'Flaherty; F Peter Guengerich; Martin Egli; Christopher J Wilds
Journal:  Biochemistry       Date:  2015-12-16       Impact factor: 3.162

2.  Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I.

Authors:  H Bates; S K Randall; C Rayssiguier; B A Bridges; M F Goodman; M Radman
Journal:  J Bacteriol       Date:  1989-05       Impact factor: 3.490

Review 3.  Translesion DNA synthesis and mutagenesis in prokaryotes.

Authors:  Robert P Fuchs; Shingo Fujii
Journal:  Cold Spring Harb Perspect Biol       Date:  2013-12-01       Impact factor: 10.005

4.  Structural and kinetic analysis of nucleoside triphosphate incorporation opposite an abasic site by human translesion DNA polymerase η.

Authors:  Amritaj Patra; Qianqian Zhang; Li Lei; Yan Su; Martin Egli; F Peter Guengerich
Journal:  J Biol Chem       Date:  2015-02-09       Impact factor: 5.157

5.  Anti-mutagenic effect of ultraviolet light on spontaneous tyrosine tRNA ochre suppressor mutations in Escherichia coli.

Authors:  R Bockrath; M Ruiz-Rubio
Journal:  Mol Gen Genet       Date:  1988-10

6.  UV-induced mutagenesis of phage S13 can occur in the absence of the RecA and UmuC proteins of Escherichia coli.

Authors:  I Tessman
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205

7.  The C-C (6-4) UV photoproduct is mutagenic in Escherichia coli.

Authors:  B W Glickman; R M Schaaper; W A Haseltine; R L Dunn; D E Brash
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

8.  Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium.

Authors:  G Storz; M F Christman; H Sies; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

9.  Discoordinate gene expression in the dnaA-dnaN operon of Escherichia coli.

Authors:  A Quiñones; W Messer
Journal:  Mol Gen Genet       Date:  1988-07

10.  Mechanism of mutation on DNA templates containing synthetic abasic sites: study with a double strand vector.

Authors:  M Takeshita; W Eisenberg
Journal:  Nucleic Acids Res       Date:  1994-05-25       Impact factor: 16.971
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.