Literature DB >> 6215339

Thymosin: an immunomodulator of antibody production in man.

A Górski, G Korczak-Kowalska, M Nowaczyk, Z Gaciong, E Skopińska-Rózewska.   

Abstract

Thymosin (TFX) stimulates polyclonal antibody synthesis of human peripheral blood, lymph node and spleen lymphocytes. This stimulation is observed only with T-cell-dependent polyclonal activators of immunoglobulin production and its mechanism appears to be associated with TFX-induced activation of T-helper cells. On the other hand, antibody production in vitro of lymphocytes already involved in high humoral responses is inhibited by thymosin. TFX has similar activity both in vitro and in vivo.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6215339      PMCID： PMC1555552     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  10 in total

1.  Suppression by thymosin of pokeweed mitogen-induced differentiation of human B cells.

Authors:  R E Wolf; A L Goldstein; M Ziff
Journal:  Clin Immunol Immunopathol       Date:  1978-11

2.  Induction of B lymphocyte colony growth in vitro by thymus-derived stimulating factor.

Authors:  B Sredni; J Gopas; L A Rozenszajn
Journal:  Eur J Immunol       Date:  1978-10       Impact factor: 5.532

3.  Induction of suppressor T cells in systemic lupus erythematosus by thymosin and cultured thymic epithelium.

Authors:  S Horowitz; W Borcherding; A V Moorthy; R Chesney; H Schulte-Wisserman; R Hong
Journal:  Science       Date:  1977-09-02       Impact factor: 47.728

4.  Human peripheral blood T lymphocyte subpopulations isolated on the basis of their affinity for sheep red blood cells differ in angiogenesis-inducing capability.

Authors:  M J Kamiński; M Nowacyk; E Skopińska-Rozewska; G Kamińska; W Bem
Journal:  Clin Exp Immunol       Date:  1981-11       Impact factor: 4.330

5.  In vitro synthesis of IgG by peripheral blood lymphocytes in chronic liver disease.

Authors:  M G Mutchnick; H M Lederman; A Missirian; A G Johnson
Journal:  Clin Exp Immunol       Date:  1981-02       Impact factor: 4.330

6.  Levamisole: possibilities of immunomodulation in the basic treatment of rheumatoid arthritis. Clinical and immunological observations in a one-year decaris treatment of rheumatoid arthritis patients.

Authors:  L Hodinka; K Merétey; Z Zahumenszky; S Bozsóky
Journal:  Ther Hung       Date:  1981

7.  The effect of calf thymus extract (TFX) on human and mouse hemopoiesis.

Authors:  A Górski; A B Skotnicki; Z Gaciong; G Korczak
Journal:  Thymus       Date:  1981-09

8.  Activation of neurosecretory cells enhances their synthesis of secretory protein.

Authors:  R W Berry; S Arch
Journal:  Brain Res       Date:  1981-06-29       Impact factor: 3.252

9.  Maturational effects of thymic hormones on human helper and suppressor T cells: effects of FTS ('Facteur Thymique Sérique') and thymosin.

Authors:  D B Kaufman
Journal:  Clin Exp Immunol       Date:  1980-03       Impact factor: 4.330

10.  Developmental changes in humoral suppressor activity released from concanavalin A-stimulated human lymphocytes on B cell differentiation.

Authors:  T Miyawaki; M Kubo; T Nagaoki; N Moriya; T Yokoi; M Mukai; N Taniguchi
Journal:  J Immunol       Date:  1981-05       Impact factor: 5.422
  10 in total
  2 in total

Review 1.  Therapeutic application of calf thymus extract (TFX).

Authors:  A B Skotnicki
Journal:  Med Oncol Tumor Pharmacother       Date:  1989

2.  The Hidden Function of Vitamin D.

Authors:  Hiba Sibaii; Salwa Refat El-Zayat; Azza Abd El-Shaheed; Nermine N Mahfouz; Sara F Sallam; Marwa H El Azma
Journal:  Open Access Maced J Med Sci       Date:  2016-11-30
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.