Literature DB >> 302032

Induction of suppressor T cells in systemic lupus erythematosus by thymosin and cultured thymic epithelium.

S Horowitz, W Borcherding, A V Moorthy, R Chesney, H Schulte-Wisserman, R Hong.   

Abstract

Patients with systemic lupus erythematosus lacked suppressor T cell function. Suppressor cell activity was induced in cells from many of these patients by incubation with thymosin or cultured thymic epithelium. These results suggest that thymic manipulation may be a useful therapeutic modality in this disease.

Entities:  

Mesh:

Substances:

Year:  1977        PMID: 302032     DOI: 10.1126/science.302032

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  37 in total

Review 1.  Thymic hormones--a clinical update.

Authors:  M B Sztein; A L Goldstein
Journal:  Springer Semin Immunopathol       Date:  1986

2.  The differential effect of in vivo hydrocortisone on the kinetics of subpopulations of human peripheral blood thymus-derived lymphocytes.

Authors:  B F Haynes; A S Fauci
Journal:  J Clin Invest       Date:  1978-03       Impact factor: 14.808

3.  Studies of immune functions of patients with systemic lupus erythematosus. Complement-dependent immunoglobulin M anti-thymus-derived cell antibodies preferentially inactivate suppressor cells.

Authors:  T Sakane; A D Steinberg; J P Reeves; I Green
Journal:  J Clin Invest       Date:  1979-05       Impact factor: 14.808

4.  Immune function in systemic lupus erythematosus. Impairment of in vitro T-cell proliferation and in vivo antibody response to exogenous antigen.

Authors:  A B Gottlieb; R G Lahita; N Chiorazzi; H G Kunkel
Journal:  J Clin Invest       Date:  1979-05       Impact factor: 14.808

5.  Altered regulation of mitogen responsiveness by suppressor cells in multiple sclerosis.

Authors:  R L Gonzalez; P C Dau; L E Spitler
Journal:  Clin Exp Immunol       Date:  1979-04       Impact factor: 4.330

6.  Suppressor-cell antibody in systemic lupus erythematosus. Possible mechanism for suppressor-cell dysfunction.

Authors:  A Sagawa; N I Abdou
Journal:  J Clin Invest       Date:  1979-03       Impact factor: 14.808

7.  Decreased circulating thymus-derived cells with receptors for the Fc portion of immunoglobulin G in systemic lupus erythematosus.

Authors:  D Alarcón-Segovia; A Ruíz-Argüelles
Journal:  J Clin Invest       Date:  1978-12       Impact factor: 14.808

8.  Long-term proliferation of mouse thymic epithelial cells in culture.

Authors:  U K Ehmann; R A Shiurba; W D Peterson
Journal:  In Vitro Cell Dev Biol       Date:  1986-12

9.  Controlled trial of a thymic hormone extract (Thymostimulin) in 'autoimmune' chronic active hepatitis.

Authors:  J E Hegarty; K T Nouri Aria; A L Eddleston; R Williams
Journal:  Gut       Date:  1984-03       Impact factor: 23.059

10.  Subpopulations of T lymphocytes in patients with ankylosing spondylitis.

Authors:  E Nilsson; G Biberfeld
Journal:  Ann Rheum Dis       Date:  1980-12       Impact factor: 19.103

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.