Literature DB >> 6206187

Two-dimensional gel electrophoretic analysis of the MT3 and DR4 molecules from the different D-typed cells.

M Suzuki, T Yabe, M Satake, T Juji, H Hamaguchi.   

Abstract

This report demonstrates directly, using two-dimensional gel electrophoresis and alloantisera, the following: (a) The DR4 light chains show a structural polymorphism among the Dw4, DKT2, and DYT cells. (b) Most of the class II light chains consist of the DR light chain. (c) The MT3 molecule is distinct from the DR4 molecule in the Dw4, DKT2, and DYT cells. (d) The MT3 molecule does not show any structural heterogeneity among the Dw4, DKT2, and DYT cells. These results suggest that the dissection of the D specificity among Dw4, DKT2, and DYT is mainly caused by the differences of the DR4 molecules.

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Year:  1984        PMID： 6206187      PMCID： PMC2187405          DOI： 10.1084/jem.160.3.751

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  12 in total

1.  High resolution two-dimensional electrophoresis of basic as well as acidic proteins.

Authors:  P Z O'Farrell; H M Goodman; P H O'Farrell
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

2.  Alloantigens of human lymphoid cell lines; 'human Ia-like antigens'. Alloantigenic activity and cell line, organ and tissue distribution as determined by radioimmunoassay.

Authors:  K Koyama; K Nakamuro; N Tanigaki; D Pressman
Journal:  Immunology       Date:  1977-08       Impact factor: 7.397

3.  Five HLA-D clusters associated with HLA-DR4.

Authors:  N L Reinsmoen; F H Bach
Journal:  Hum Immunol       Date:  1982-06       Impact factor: 2.850

4.  Serologic dissection of HLA-D specificities by the use of monoclonal antibodies.

Authors:  M Kasahara; T Takenouchi; K Ogasawara; H Ikeda; T Okuyama; N Ishikawa; J Moriuchi; A Wakisaka; Y Kikuchi; M Aizawa; T Kaneko; N Kashiwagi; Y Nishimura; T Sasazuki
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

5.  Separation of three class II antigens from a homozygous human B cell line.

Authors:  D A Shackelford; L A Lampson; J L Strominger
Journal:  J Immunol       Date:  1983-01       Impact factor: 5.422

6.  Biosynthesis and maturation of HLA-DR antigens in vivo.

Authors:  M J Owen; A M Kissonerghis; H F Lodish; M J Crumpton
Journal:  J Biol Chem       Date:  1981-09-10       Impact factor: 5.157

7.  Structural polymorphism of the DC1 light chains from DR1-, DR2-, and DRw6-positive cell lines.

Authors:  D A Shackelford; B Eibl; J L Strominger
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

8.  Effect of anti-HLA antisera on macrophage-T-cell interactions.

Authors:  R S Geha; H Milgrom; M Broff; S Alpert; S Martin; E J Yunis
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

9.  Further characterization of HLA-DS molecules: implications for studies assessing the role of human Ia molecules in cell interactions and disease susceptibility.

Authors:  S M Goyert; J Silver
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

10.  Dw/LD-related molecular polymorphism of DR4 beta-chains.

Authors:  J P Groner; A J Watson; F H Bach
Journal:  J Exp Med       Date:  1983-05-01       Impact factor: 14.307
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  6 in total

1.  Molecular characterization of MT3 antigens by two-dimensional gel electrophoresis, NH2-terminal amino acid sequence analysis, and southern blot analysis.

Authors:  R Sorrentino; J Lillie; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1985-06       Impact factor: 11.205

2.  Two DR beta allelic series defined by exon II-specific synthetic oligonucleotide genomic hybridization: a method of HLA typing?

Authors:  I Le Gall; P Millasseau; J Dausset; D Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

3.  Evolutionary and genetic implications of sequence variation in two nonallelic HLA-DR beta-chain cDNA sequences.

Authors:  J M Curtsinger; J M Hilden; J S Cairns; F H Bach
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

4.  The molecular basis for HLA class II associations with rheumatoid arthritis.

Authors:  G T Nepom; J A Hansen; B S Nepom
Journal:  J Clin Immunol       Date:  1987-01       Impact factor: 8.317

5.  The MT3 specificity resides on a novel human class II antigen distinct from the HLA-DR antigen and DC-like antigen.

Authors:  T Yabe; M Suzuki; M Satake; T Juji; H Hamaguchi
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846

6.  Specific genomic markers for the HLA-DQ subregion discriminate between DR4+ insulin-dependent diabetes mellitus and DR4+ seropositive juvenile rheumatoid arthritis.

Authors:  B S Nepom; J Palmer; S J Kim; J A Hansen; S L Holbeck; G T Nepom
Journal:  J Exp Med       Date:  1986-07-01       Impact factor: 14.307
  6 in total

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