Literature DB >> 6204884

The cytogenetic efficiency of the antitumor agents bleomycin and peplomycin is enhanced by the heart drug verapamil (isoptin).

W Scheid, B Oppermann, H Traut.   

Abstract

The induction of 2-break chromosome aberrations (dicentrics and ring chromosomes) in human lymphocytes by the antitumor agents bleomycin and peplomycin is strongly enhanced when those agents are applied together with the heart drug verapamil (isoptin).

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Year:  1984        PMID： 6204884     DOI： 10.1007/bf01949756

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  2 in total

1.  Potentiation of bleomycin cytotoxicity by membrane-interacting drugs and increased calcium ions.

Authors:  S Mizuno; A Ishida
Journal:  Biochem Biophys Res Commun       Date:  1982-08       Impact factor: 3.575

2.  The cytogenetic effect of bleomycin on human peripheral lymphocytes in vitro and in vivo.

Authors:  J Dresp; E Schmid; M Bauchinger
Journal:  Mutat Res       Date:  1978-01       Impact factor: 2.433
  2 in total
  2 in total

1.  Enhancement of the cytogenetic efficacy of the antitumor agent bleomycin by the calcium and calmodulin antagonist fendiline.

Authors:  W Scheid; H Traut
Journal:  Experientia       Date:  1988-03-15

Review 2.  Mechanisms of bleomycin-induced lung damage.

Authors:  J Hay; S Shahzeidi; G Laurent
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153
  2 in total

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