Literature DB >> 2450775

Enhancement of the cytogenetic efficacy of the antitumor agent bleomycin by the calcium and calmodulin antagonist fendiline.

W Scheid1, H Traut.   

Abstract

The induction of chromosome aberrations (dicentric and ring chromosomes) in human lymphocytes by the antitumor agent bleomycin is synergistically enhanced when bleomycin is applied together with the calcium antagonist fendiline (Sensit).

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Year:  1988        PMID： 2450775     DOI： 10.1007/bf01941716

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

1.  Drug resistance of cancer cells probed.

Authors:  J L Marx
Journal:  Science       Date:  1986-11-14       Impact factor: 47.728

2.  The anticancer agent adriamycin can be actively cytotoxic without entering cells.

Authors:  T R Triton; G Yee
Journal:  Science       Date:  1982-07-16       Impact factor: 47.728

Review 3.  Fendiline: a review of its basic pharmacological and clinical properties.

Authors:  R Bayer; R Mannhold
Journal:  Pharmatherapeutica       Date:  1987

4.  Verapamil enhancement of chemotherapeutic efficacy in human bladder cancer cells.

Authors:  W G Simpson; M T Tseng; K C Anderson; J I Harty
Journal:  J Urol       Date:  1984-09       Impact factor: 7.450

5.  Reversal of adriamycin resistance by verapamil in human ovarian cancer.

Authors:  A M Rogan; T C Hamilton; R C Young; R W Klecker; R F Ozols
Journal:  Science       Date:  1984-06-01       Impact factor: 47.728

6.  Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients.

Authors:  R F Ozols; R E Cunnion; R W Klecker; T C Hamilton; Y Ostchega; J E Parrillo; R C Young
Journal:  J Clin Oncol       Date:  1987-04       Impact factor: 44.544

7.  Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

Authors:  T Tsuruo; H Iida; S Tsukagoshi; Y Sakurai
Journal:  Cancer Res       Date:  1981-05       Impact factor: 12.701

8.  Effects of verapamil on in vitro intracellular accumulation and retention of daunorubicin in blast cells from patients with acute nonlymphocytic leukemia.

Authors:  D D Ross; C C Joneckis; C A Schiffer
Journal:  Blood       Date:  1986-07       Impact factor: 22.113

9.  Verapamil-mediated sensitization of doxorubicin-selected pleiotropic resistance in human sarcoma cells: selectivity for drugs which produce DNA scission.

Authors:  W G Harker; D Bauer; B B Etiz; R A Newman; B I Sikic
Journal:  Cancer Res       Date:  1986-05       Impact factor: 12.701

10.  The cytogenetic efficiency of the antitumor agents bleomycin and peplomycin is enhanced by the heart drug verapamil (isoptin).

Authors:  W Scheid; B Oppermann; H Traut
Journal:  Experientia       Date:  1984-07-15
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