Literature DB >> 6199793

Developmental regulation of cytokeratins in cells of the rat mammary gland studied with monoclonal antibodies.

R Allen, R Dulbecco, P Syka, M Bowman, B Armstrong.   

Abstract

We have isolated two monoclonal antibodies to cytokeratins and determined their cell specificities. They display interesting localization within the rat mammary gland. One (1A10) shows specificity for myoepithelial cells; the other (24B42) is specific for lumenal cells at various stages of development. These two monoclonal antibodies and three others to cytokeratin previously isolated were used in conjunction with antibodies to myosin and collagen IV to confirm and extend our previous findings on epithelial cell types and development within the mammary gland.

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Year:  1984        PMID： 6199793      PMCID： PMC344794          DOI： 10.1073/pnas.81.4.1203

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  17 in total

1.  Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes.

Authors:  A F Williams; G Galfrè; C Milstein
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

2.  Biochemical and immunological identification of cytokeratin proteins present in hepatocytes of mammalian liver tissue.

Authors:  W W Franke; H Denk; R Kalt; E Schmid
Journal:  Exp Cell Res       Date:  1981-02       Impact factor: 3.905

3.  "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.

Authors:  W N Burnette
Journal:  Anal Biochem       Date:  1981-04       Impact factor: 3.365

4.  Immunohistochemical localization of keratin in normal human tissues.

Authors:  R Schlegel; S Banks-Schlegel; G S Pinkus
Journal:  Lab Invest       Date:  1980-01       Impact factor: 5.662

5.  Identification of mouse mammary epithelial cells by immunofluorescence with rabbit and guinea pig antikeratin antisera.

Authors:  B B Asch; N A Burstein; A Vidrich; T T Sun
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

6.  Keratin-like proteins in normal and neoplastic cells of human and rat mammary gland as revealed by immunofluorescence microscopy.

Authors:  R Krepler; H Denk; E Weirich; E Schmid; W W Franke
Journal:  Differentiation       Date:  1981       Impact factor: 3.880

7.  Correlation of specific keratins with different types of epithelial differentiation: monoclonal antibody studies.

Authors:  S C Tseng; M J Jarvinen; W G Nelson; J W Huang; J Woodcock-Mitchell; T T Sun
Journal:  Cell       Date:  1982-09       Impact factor: 41.582

8.  Intermediate-sized filaments of the prekeratin type in myoepithelial cells.

Authors:  W W Franke; E Schmid; C Freudenstein; B Appelhans; M Osborn; K Weber; T W Keenan
Journal:  J Cell Biol       Date:  1980-03       Impact factor: 10.539

9.  Monoclonal antibodies provide specific intramolecular markers for the study of epithelial tonofilament organization.

Authors:  E B Lane
Journal:  J Cell Biol       Date:  1982-03       Impact factor: 10.539

10.  Detection of a cytokeratin determinant common to diverse epithelial cells by a broadly cross-reacting monoclonal antibody.

Authors:  O Gigi; B Geiger; Z Eshhar; R Moll; E Schmid; S Winter; D L Schiller; W W Franke
Journal:  EMBO J       Date:  1982       Impact factor: 11.598
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  9 in total

1.  Monoclonal antibody that defines human myoepithelium.

Authors:  S H Dairkee; C Blayney; H S Smith; A J Hackett
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

2.  The rat gene homologous to the human gene 9-27 is involved in the development of the mammary gland.

Authors:  I Zucchi; C Montagna; L Susani; P Vezzoni; R Dulbecco
Journal:  Proc Natl Acad Sci U S A       Date:  1998-02-03       Impact factor: 11.205

3.  Stochastic development of invasive potential in rat mammary tumors induced by N-methyl-N-nitrosourea.

Authors:  R Dulbecco; B Armstrong
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

4.  Reversion toward an earlier stage of differentiation and loss of polarity during progression of N-methyl-N-nitrosourea-induced rat mammary tumours.

Authors:  R Dulbecco; B Armstrong; R Allen
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

5.  Microvillin: a 200-kilodalton protein in microvilli of rat mammary cells detected by a monoclonal antibody.

Authors:  R Allen; R Dulbecco; P Syka; M Bowman
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205

6.  Lumen formation and redistribution of inframembranous proteins during differentiation of ducts in the rat mammary gland.

Authors:  R Dulbecco; W R Allen; M Bowman
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205

Review 7.  Stem cells and the development of mammary cancers in experimental rats and in humans.

Authors:  P S Rudland
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

8.  Immunolocalization of the human basal epithelial marker monoclonal antibody 312C8-1 in normal tissue and mammary tumours of rodents.

Authors:  A Tsubura; T Inui; H Senzaki; S Morii; S H Dairkee
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

9.  Organization of cytokeratin bundles by desmosomes in rat mammary cells.

Authors:  M Bologna; R Allen; R Dulbecco
Journal:  J Cell Biol       Date:  1986-02       Impact factor: 10.539
  9 in total

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