Literature DB >> 6198202

Development of a new tachykinin antagonist.

R Mathison, P Stofer, F Barja, H Immer.   

Abstract

The mouse urinary bladder possesses a tachykinin receptor which responds to kassinin and eledoisin, but not to some other tachykinins. The action of kassinin, but not that of eledoisin, was blocked in a surmountable manner by a new tachykinin antagonist, D-Pro4, Val8, D-Trp (SP).

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Year:  1984        PMID: 6198202     DOI: 10.1007/bf01959116

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  8 in total

1.  Everted portal vein: a sensitive model for studies of vasoactive compounds.

Authors:  D Mastrangelo; R Mathison
Journal:  J Cardiovasc Pharmacol       Date:  1983 Jan-Feb       Impact factor: 3.105

2.  Further evidence for multiple tachykinin receptors.

Authors:  J W Growcott; A Jamieson; A V Tarpey; L D Topham
Journal:  Eur J Pharmacol       Date:  1982-12-17       Impact factor: 4.432

3.  Substance P antagonists active in vitro and in vivo.

Authors:  J Mizrahi; E Escher; S Caranikas; P D'orléans-Juste; D Regoli
Journal:  Eur J Pharmacol       Date:  1982-08-13       Impact factor: 4.432

4.  Pharmacological characterization of four related substance P antagonists.

Authors:  U Björkroth; S Rosell; J C Xu; K Folkers
Journal:  Acta Physiol Scand       Date:  1982-10

5.  Antagonists of substance P.

Authors:  S Caranikas; J Mizrahi; P D'Orléans-Juste; D Regoli
Journal:  Eur J Pharmacol       Date:  1982-01-22       Impact factor: 4.432

6.  In vitro activities of some synthetic substance P analogs.

Authors:  R E Chipkin; J M Stewart; V E Sweeney; K Harris; R Williams
Journal:  Arch Int Pharmacodyn Ther       Date:  1979-08

7.  Agonist effects of [D-Pro2,D-Phe7,D-Trp9]substance P--evidence for different receptors.

Authors:  A B Hawcock; A G Hayes; M B Tyers
Journal:  Eur J Pharmacol       Date:  1982-05-07       Impact factor: 4.432

8.  The mechanism of action of a substance P antagonist (D-Pro2, D-Trp7,9)-SP.

Authors:  R Håkanson; J Hörig; S Leander
Journal:  Br J Pharmacol       Date:  1982-12       Impact factor: 8.739

  8 in total

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