Literature DB >> 6197678

Cerebrospinal fluid monoamine metabolites in patients with infantile spasms.

F Silverstein, M V Johnston.   

Abstract

We measured CSF levels of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) by high-performance liquid chromatography in seven children with infantile spasms and in a group of age- and sex-matched controls. The mean concentration of the serotonin metabolite 5-HIAA was 40% (p less than 0.01) lower in the infantile spasms group as compared with controls; HVA levels were similar in both groups. The data provide additional evidence that serotonin metabolism is abnormal in patients with infantile spasms.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6197678     DOI： 10.1212/wnl.34.1.102

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  16 in total

1.  Seizures and steroids.

Authors:  R O Robinson
Journal:  Arch Dis Child       Date:  1985-02       Impact factor: 3.791

Review 2.  Inflammation in Epileptic Encephalopathies.

Authors:  Oleksii Shandra; Solomon L Moshé; Aristea S Galanopoulou
Journal:  Adv Protein Chem Struct Biol       Date:  2017-02-28       Impact factor: 3.507

3.  A patient with infantile spasms and low homovanillic acid levels in cerebrospinal fluid: L-dopa dependent seizures?

Authors:  H Sugie; Y Sugie; N Kato; Y Fukuyama
Journal:  Eur J Pediatr       Date:  1989-06       Impact factor: 3.183

Review 4.  Pathogenesis and new candidate treatments for infantile spasms and early life epileptic encephalopathies: A view from preclinical studies.

Authors:  Aristea S Galanopoulou; Solomon L Moshé
Journal:  Neurobiol Dis       Date:  2015-05-09       Impact factor: 5.996

5.  Reduced urinary serotonin excretion after intake of high doses of hypoxanthine.

Authors:  H Manzke; H Gustmann
Journal:  Eur J Pediatr       Date:  1989-01       Impact factor: 3.183

6.  Serotonin reduction in the mouse neostriatum during hyperthermia-induced convulsions studied by immunohistochemistry.

Authors:  Y Takeuchi; K Fujiwara; K Ishimura; H Yoshioka; T Sawada
Journal:  Acta Neuropathol       Date:  1988       Impact factor: 17.088

7.  A model of symptomatic infantile spasms syndrome.

Authors:  Morris H Scantlebury; Aristea S Galanopoulou; Lenka Chudomelova; Emmanuel Raffo; David Betancourth; Solomon L Moshé
Journal:  Neurobiol Dis       Date:  2009-11-26       Impact factor: 5.996

Review 8.  Basic mechanisms of catastrophic epilepsy -- overview from animal models.

Authors:  Aristea S Galanopoulou
Journal:  Brain Dev       Date:  2013-01-11       Impact factor: 1.961

9.  Dementia presenting with aphasia: clinical characteristics.

Authors:  M F Mendez; B A Zander
Journal:  J Neurol Neurosurg Psychiatry       Date:  1991-06       Impact factor: 10.154

Review 10.  Pathophysiology of massive infantile spasms: perspective on the putative role of the brain adrenal axis.

Authors:  T Z Baram
Journal:  Ann Neurol       Date:  1993-03       Impact factor: 10.422
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.