Literature DB >> 6193834

Selective inhibition of retrograde axonal transport by erythro-9-[3-(2-hydroxynonyl)]adenine.

D S Forman, K J Brown, M E Promersberger.   

Abstract

Retrograde transport of microscopically visible organelles in isolated lobster axons was selectively inhibited by erythro-9-[3-(2-hydroxynonyl)]adenine (EHNA), with little or no effect on anterograde transport. The retrograde velocity was reduced both in living axons and in permeabilized axons in which movement was reactivated with exogenous ATP. This is the first report of an agent that selectively inhibits axonal transport in one direction.

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Year:  1983        PMID： 6193834     DOI： 10.1016/0006-8993(83)90381-5

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  9 in total

Review 1.  The axonal transport of mitochondria.

Authors:  Peter J Hollenbeck; William M Saxton
Journal:  J Cell Sci       Date:  2005-12-01       Impact factor: 5.285

2.  Differential suppression of axoplasmic transport: effects of light irradiation to the growth cone of cultured dorsal root ganglion neurons.

Authors:  M Kano; H Tashiro; T Kawakami; T Takenaka; H Gotoh
Journal:  Cell Mol Neurobiol       Date:  1995-06       Impact factor: 5.046

3.  erythro-9-[3-(2-Hydroxynonyl)]adenine is an effective inhibitor of cell motility and actin assembly.

Authors:  M Schliwa; R M Ezzell; U Euteneuer
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205

4.  Effect of a dynein inhibitor on vasopressin action in toad urinary bladder.

Authors:  D Marples; B Barber; A Taylor
Journal:  J Physiol       Date:  1996-02-01       Impact factor: 5.182

5.  A novel microtubule-associated protein from mammalian nerve shows ATP-sensitive binding to microtubules.

Authors:  P J Hollenbeck; K Chapman
Journal:  J Cell Biol       Date:  1986-10       Impact factor: 10.539

6.  Microinjected fluorescent polystyrene beads exhibit saltatory motion in tissue culture cells.

Authors:  M C Beckerle
Journal:  J Cell Biol       Date:  1984-06       Impact factor: 10.539

7.  Interaction of actin filaments with microtubules.

Authors:  T D Pollard; S C Selden; P Maupin
Journal:  J Cell Biol       Date:  1984-07       Impact factor: 10.539

8.  Sertoli cell processes have axoplasmic features: an ordered microtubule distribution and an abundant high molecular weight microtubule-associated protein (cytoplasmic dynein).

Authors:  M D Neely; K Boekelheide
Journal:  J Cell Biol       Date:  1988-11       Impact factor: 10.539

Review 9.  Impaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron Degeneration.

Authors:  Brittany M Edens; Nimrod Miller; Yong-Chao Ma
Journal:  Front Cell Neurosci       Date:  2016-03-03       Impact factor: 5.505
  9 in total

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