Effect of bursa Fabricius extracts on antibody production in bursectomized or bursal cell autografted chickens.

Restoration and enhancement of immune response against BSA antigen was achieved by 5-day consecutive doses of BF estract from 4-5-week-old chickens, in birds which had been surgically bursectomized or given BF-cell autografts at 17 days of age. A similar 5-day treatment with other tissue extract, i.e. liver, spleen, pancreas or intestine, or with LPS of E. coli, in contrast, failed to provide such restoration or enhancement.