Literature DB >> 14250327

BURSA OF FABRICIUS IN CHICKENS: POSSIBLE HUMORAL FACTOR.

R L STPIERRE, G A ACKERMAN.   

Abstract

Chicks bursectomized by testosterone injection on the 5th day of incubation showed a marked inability to produce antibodies to Salmonella typhimurium. When portions of the bursa of Fabricius were enclosed in cell-impermeable Millipore diffusion chambers and implanted subcutaneously or intraperitoneally, the antibody-producing capacity of these animals was restored. Evidence strongly suggests that the bursa of Fabricius elaborates a non-cellular agent capable of restoring immunologic reactivity in bursectomized chicks.

Entities:  

Keywords:  ANTIBODY FORMATION; CHICK EMBRYO; EXPERIMENTAL LAB STUDY; IMMUNIZATION; LYMPHOID TISSUE; PHARMACOLOGY; PHYSIOLOGY, COMPARATIVE; POULTRY; SALMONELLA TYPHIMURIUM; TESTOSTERONE

Mesh：

Substances：

Year:  1965        PMID： 14250327     DOI： 10.1126/science.147.3663.1307

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  11 in total

Review 1.  Immunoglobulins and the gut.

Authors:  E A Jones
Journal:  Gut       Date:  1972-10       Impact factor: 23.059

2.  Immune globulin production by the bursa of Fabricius of young chickens.

Authors:  G J Thorbecke; N L Warner; G M Hochwald; S H Ohanian
Journal:  Immunology       Date:  1968-07       Impact factor: 7.397

3.  The restoration of the glycaemic response to adrenaline in the bursectomized fowl.

Authors:  B M Freeman
Journal:  Experientia       Date:  1972-06-15

Review 4.  Immunological activity of the thymus.

Authors: 
Journal:  Can Med Assoc J       Date:  1966-03-05       Impact factor: 8.262

5.  Effect of bursa Fabricius extracts on antibody production in bursectomized or bursal cell autografted chickens.

Authors:  T Baba; Y Okuno
Journal:  Immunology       Date:  1976-10       Impact factor: 7.397

6.  Restoration of autoimmune thyroiditis in bursectomized-irradiated OS chickens by bursa cells.

Authors:  L A Nilsson; N R Rose
Journal:  Immunology       Date:  1972-01       Impact factor: 7.397

7.  The significance of the bursa of Fabricius in relation to the synthesis of 7S and 19S immune globulins and specific antibody activity in the fowl.

Authors:  A E Pierce; R C Chubb; P L Long
Journal:  Immunology       Date:  1966-04       Impact factor: 7.397

8.  Antibody production in bursectomized chickens treated with lipid and protein fractions from bursa, thymus and liver.

Authors:  B D Jankovic; K Isakovic; J Horvat
Journal:  Experientia       Date:  1967-12-15

9.  Ontogeny of bursal function in chicken. 3. Immunocompletent cell for humoral immunity.

Authors:  P Toivanen; A Toivanen; R A Good
Journal:  J Exp Med       Date:  1972-10-01       Impact factor: 14.307

Review 10.  The functions of the thymus.

Authors:  D Osoba
Journal:  Can Med Assoc J       Date:  1966-03-05       Impact factor: 8.262
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