| Literature DB >> 6192305 |
C F Lanata, M M Levine, C Ristori, R E Black, L Jimenez, M Salcedo, J Garcia, V Sotomayor.
Abstract
A passive haemagglutination assay measuring antibody to highly purified Vi antigen, known to be sensitive and specific for the detection of chronic Salmonella typhi carriers in a non-endemic area, was assessed in an endemic area. A reciprocal serum Vi antibody titre of 160 was found to have a sensitivity of 75%, specificity of 92%, and a high predictive value in screening for chronic S typhi carriers in high-risk population group (eg, women over 40 years). This simple assay can screen for chronic S typhi carriers even in areas where typhoid fever is highly endemic.Entities:
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Year: 1983 PMID： 6192305 DOI： 10.1016/s0140-6736(83)90401-4
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321