Literature DB >> 1937790

Immunogenicity of Salmonella typhi Ty21a vaccine for young children.

J R Murphy1, L Grez, L Schlesinger, C Ferreccio, S Baqar, C Muñoz, S S Wasserman, G Losonsky, J G Olson, M M Levine.   

Abstract

An attenuated Salmonella typhi Ty21a vaccine was administered to 18 infants and toddlers (less than or equal to 24 months old) to determine its safety and immunogenicity. The vaccination (10(9) CFU per dose, three doses) was well tolerated. However, after the vaccination there was no evidence of a humoral or cellular immune response to S. typhi. The vaccine used was known to be immunogenic for older children and adults. The results support the view that the immunogenicity of Ty21a is age dependent.

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Year:  1991        PMID： 1937790      PMCID： PMC259034          DOI： 10.1128/iai.59.11.4291-4293.1991

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  19 in total

1.  CONTROLLED FIELD TRIAL IN BRITISH GUIANA SCHOOL CHILDREN OF HEAT-KILLED-PHENOLIZED AND ACETONE-KILLED LYOPHILIZED TYPHOID VACCINES.

Authors:  M T ASHCROFT; J M RITCHIE; C C NICHOLSON
Journal:  Am J Hyg       Date:  1964-03

2.  Safety and immunogenicity of two Salmonella typhi Vi capsular polysaccharide vaccines.

Authors:  C O Tacket; C Ferreccio; J B Robbins; C M Tsai; D Schulz; M Cadoz; A Goudeau; M M Levine
Journal:  J Infect Dis       Date:  1986-08       Impact factor: 5.226

3.  Characteristics of humoral and cellular immunity to Salmonella typhi in residents of typhoid-endemic and typhoid-free regions.

Authors:  J R Murphy; S Baqar; C Muñoz; L Schlesinger; C Ferreccio; A A Lindberg; S Svenson; G Losonsky; F Koster; M M Levine
Journal:  J Infect Dis       Date:  1987-12       Impact factor: 5.226

4.  Large-scale field trial of Ty21a live oral typhoid vaccine in enteric-coated capsule formulation.

Authors:  M M Levine; C Ferreccio; R E Black; R Germanier
Journal:  Lancet       Date:  1987-05-09       Impact factor: 79.321

5.  A controlled field trial of live Salmonella typhi strain Ty 21a oral vaccine against typhoid: three-year results.

Authors:  M H Wahdan; C Sérié; Y Cerisier; S Sallam; R Germanier
Journal:  J Infect Dis       Date:  1982-03       Impact factor: 5.226

6.  Evaluation of a UDP-glucose-4-epimeraseless mutant of Salmonella typhi as a liver oral vaccine.

Authors:  R H Gilman; R B Hornick; W E Woodard; H L DuPont; M J Snyder; M M Levine; J P Libonati
Journal:  J Infect Dis       Date:  1977-12       Impact factor: 5.226

7.  Safety, infectivity, immunogenicity, and in vivo stability of two attenuated auxotrophic mutant strains of Salmonella typhi, 541Ty and 543Ty, as live oral vaccines in humans.

Authors:  M M Levine; D Herrington; J R Murphy; J G Morris; G Losonsky; B Tall; A A Lindberg; S Svenson; S Baqar; M F Edwards
Journal:  J Clin Invest       Date:  1987-03       Impact factor: 14.808

8.  Construction of a potential bivalent vaccine strain: introduction of Shigella sonnei form I antigen genes into the galE Salmonella typhi Ty21a typhoid vaccine strain.

Authors:  S B Formal; L S Baron; D J Kopecko; O Washington; C Powell; C A Life
Journal:  Infect Immun       Date:  1981-12       Impact factor: 3.441

9.  Vi serology in detection of chronic Salmonella typhi carriers in an endemic area.

Authors:  C F Lanata; M M Levine; C Ristori; R E Black; L Jimenez; M Salcedo; J Garcia; V Sotomayor
Journal:  Lancet       Date:  1983-08-20       Impact factor: 79.321

10.  Immunogenicity of Ty21a attenuated "Salmonella typhi" given with sodium bicarbonate or in enteric-coated capsules.

Authors:  R Black; M M Levine; C Young; J Rooney; S Levine; M L Clements; S O'Donnell; T Hugues; R Germanier
Journal:  Dev Biol Stand       Date:  1983
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  11 in total

Review 1.  Vaccination against Salmonella Infection: the Mucosal Way.

Authors:  Rémi Gayet; Gilles Bioley; Nicolas Rochereau; Stéphane Paul; Blaise Corthésy
Journal:  Microbiol Mol Biol Rev       Date:  2017-06-14       Impact factor: 11.056

2.  TTSS2-deficient hha mutant of Salmonella Typhimurium exhibits significant systemic attenuation in immunocompromised hosts.

Authors:  Vikalp Vishwakarma; Niladri Bhusan Pati; Shilpa Ray; Susmita Das; Mrutyunjay Suar
Journal:  Virulence       Date:  2014-01-08       Impact factor: 5.882

3.  Engineering, conjugation, and immunogenicity assessment of Escherichia coli O121 O antigen for its potential use as a typhoid vaccine component.

Authors:  Michael Wetter; Michael Kowarik; Michael Steffen; Paula Carranza; Giampietro Corradin; Michael Wacker
Journal:  Glycoconj J       Date:  2012-10-06       Impact factor: 2.916

4.  Safety and immunogenicity of Salmonella typhi Ty21a vaccine in young Thai children.

Authors:  S J Cryz; N Vanprapar; U Thisyakorn; T Olanratmanee; G Losonsky; M M Levine; S Chearskul
Journal:  Infect Immun       Date:  1993-03       Impact factor: 3.441

5.  Mucosal priming of newborn mice with S. Typhi Ty21a expressing anthrax protective antigen (PA) followed by parenteral PA-boost induces B and T cell-mediated immunity that protects against infection bypassing maternal antibodies.

Authors:  Karina Ramirez; Yanina Ditamo; James E Galen; Les W J Baillie; Marcela F Pasetti
Journal:  Vaccine       Date:  2010-07-07       Impact factor: 3.641

6.  Specific lung mucosal and systemic immune responses after oral immunization of mice with Salmonella typhimurium aroA, Salmonella typhi Ty21a, and invasive Escherichia coli expressing recombinant pertussis toxin S1 subunit.

Authors:  M J Walker; M Rohde; K N Timmis; C A Guzmán
Journal:  Infect Immun       Date:  1992-10       Impact factor: 3.441

Review 7.  Vaccination against typhoid fever: present status.

Authors:  B Ivanoff; M M Levine; P H Lambert
Journal:  Bull World Health Organ       Date:  1994       Impact factor: 9.408

8.  Safety and immunogenicity of Vi conjugate vaccines for typhoid fever in adults, teenagers, and 2- to 4-year-old children in Vietnam.

Authors:  Z Kossaczka; F Y Lin; V A Ho; N T Thuy; P Van Bay; T C Thanh; H B Khiem; D D Trach; A Karpas; S Hunt; D A Bryla; R Schneerson; J B Robbins; S C Szu
Journal:  Infect Immun       Date:  1999-11       Impact factor: 3.609

Review 9.  Vaccines for preventing typhoid fever.

Authors:  Rachael Milligan; Mical Paul; Marty Richardson; Ami Neuberger
Journal:  Cochrane Database Syst Rev       Date:  2018-05-31

Review 10.  Vaccines against invasive Salmonella disease: current status and future directions.

Authors:  Calman A MacLennan; Laura B Martin; Francesca Micoli
Journal:  Hum Vaccin Immunother       Date:  2014-05-07       Impact factor: 3.452
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