Literature DB >> 6190011

Topography of murine leukemia virus envelope proteins: characterization of transmembrane components.

A Pinter, W J Honnen.   

Abstract

Trypsinization of intact Moloney murine leukemia virus resulted in cleavage of p15(E) and Pr15(E) at a site near the middle of the molecule, producing a 9,000-dalton amino-terminal fragment which contains the disulfide linkage site to gp70 and which carries p15(E) epitopes b and c, but not epitope a. After solubilization of the viral membrane, trypsinization occurred at a second site within 1,000 daltons of the carboxy end of p15(E). This site is not exposed in intact virions, indicating that p15(E) and Pr15(E) are transmembrane proteins.

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Year:  1983        PMID： 6190011      PMCID： PMC256584     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  The nature of the association between the murine leukemia virus envelope proteins.

Authors:  A Pinter; J Lieman-Hurwitz; E Fleissner
Journal:  Virology       Date:  1978-12       Impact factor: 3.616

2.  Virus-specific precursor polypeptides in cells infected with Rauscher leukemia virus: synthesis, identification, and processing.

Authors:  D Van Zaane; J A Dekker-Michielsen; H P Bloemers
Journal:  Virology       Date:  1976-11       Impact factor: 3.616

3.  The presence of disulfide-linked gp70-p15(E) complexes in AKR murine leukemia virus.

Authors:  A Pinter; E Fleissner
Journal:  Virology       Date:  1977-12       Impact factor: 3.616

4.  An analysis of type-C retrovirus polypeptides and their associations in the virion.

Authors:  R C Montelaro; S J Sullivan; D P Bolognesi
Journal:  Virology       Date:  1978-01       Impact factor: 3.616

5.  Monoclonal antibodies against murine leukemia viruses: identification of six antigenic determinants on the p 15(E) and gp70 envelope proteins.

Authors:  M E Lostrom; M R Stone; M Tam; W N Burnette; A Pinter; R C Nowinski
Journal:  Virology       Date:  1979-10-30       Impact factor: 3.616

6.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

7.  Topological mapping of murine leukemia virus proteins by competition-binding assays with monoclonal antibodies.

Authors:  M R Stone; R C Nowinski
Journal:  Virology       Date:  1980-01-30       Impact factor: 3.616

8.  Presence of murine leukemia virus envelope proteins gp70 and p15(E) in a common polyprotein of infected cells.

Authors:  N G Famulari; D L Buchhagen; H D Klenk; E Fleissner
Journal:  J Virol       Date:  1976-11       Impact factor: 5.103

9.  High molecular weight precursor polypeptides to structural proteins of Rauscher murine leukemia virus.

Authors:  S Z Shapiro; M Strand; J T August
Journal:  J Mol Biol       Date:  1976-11-15       Impact factor: 5.469

10.  A fucose-deficient glycoprotein precursor to Rauscher leukemia virus gp69/71.

Authors:  R B Naso; L J Arcement; W L Karshin; G A Jamjoom; R B Arlinghaus
Journal:  Proc Natl Acad Sci U S A       Date:  1976-07       Impact factor: 11.205
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  24 in total

1.  The role of the membrane-spanning domain sequence in glycoprotein-mediated membrane fusion.

Authors:  G M Taylor; D A Sanders
Journal:  Mol Biol Cell       Date:  1999-09       Impact factor: 4.138

2.  Receptor choice determinants in the envelope glycoproteins of amphotropic, xenotropic, and polytropic murine leukemia viruses.

Authors:  J L Battini; J M Heard; O Danos
Journal:  J Virol       Date:  1992-03       Impact factor: 5.103

3.  Role of the cytoplasmic tail of ecotropic moloney murine leukemia virus Env protein in fusion pore formation.

Authors:  G B Melikyan; R M Markosyan; S A Brener; Y Rozenberg; F S Cohen
Journal:  J Virol       Date:  2000-01       Impact factor: 5.103

4.  Identification of point mutations in the envelope gene of Moloney murine leukemia virus TB temperature-sensitive paralytogenic mutant ts1: molecular determinants for neurovirulence.

Authors:  P F Szurek; P H Yuen; R Jerzy; P K Wong
Journal:  J Virol       Date:  1988-01       Impact factor: 5.103

5.  Fv-4: identification of the defect in Env and the mechanism of resistance to ecotropic murine leukemia virus.

Authors:  G M Taylor; Y Gao; D A Sanders
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

Review 6.  Library screening and receptor-directed targeting of gammaretroviral vectors.

Authors:  Peter M Mazari; Monica J Roth
Journal:  Future Microbiol       Date:  2013-01       Impact factor: 3.165

7.  Processing of the glycoprotein of feline immunodeficiency virus: effect of inhibitors of glycosylation.

Authors:  E B Stephens; E Monck; K Reppas; E J Butfiloski
Journal:  J Virol       Date:  1991-03       Impact factor: 5.103

8.  The hypervariable domain of the murine leukemia virus surface protein tolerates large insertions and deletions, enabling development of a retroviral particle display system.

Authors:  S C Kayman; H Park; M Saxon; A Pinter
Journal:  J Virol       Date:  1999-03       Impact factor: 5.103

9.  Molecular cloning of biologically active Rauscher spleen focus-forming virus and the sequences of its env gene and long terminal repeat.

Authors:  R K Bestwick; B A Boswell; D Kabat
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

10.  Analysis of the functional and host range-determining regions of the murine ectropic and amphotropic retrovirus envelope proteins.

Authors:  R A Morgan; O Nussbaum; D D Muenchau; L Shu; L Couture; W F Anderson
Journal:  J Virol       Date:  1993-08       Impact factor: 5.103
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