Literature DB >> 6189946

Identification, purification, and characterization of antigen-activated and antigen-specific human B lymphocytes.

J H Kehrl, A S Fauci.   

Abstract

Activated pneumococcal polysaccharide (PPS)-specific human B lymphocytes have been purified and examined in vitro. They are large cells that are refractory to further activation by antigen, anti-Ig, or Staphylococcus aureus Cowan strain I, but they respond directly by proliferation to B cell growth factors. In addition, they express the isotype pattern of activated cells and a surface marker of activated lymphocytes called 4F2. Finally, they contain a subset of cells that spontaneously secrete PPS-specific antibody.

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Year:  1983        PMID： 6189946      PMCID： PMC2187019          DOI： 10.1084/jem.157.5.1692

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  15 in total

Review 1.  A third signal in B cell activation given by TRF.

Authors:  A Schimpl; E Wecker
Journal:  Transplant Rev       Date:  1975

2.  Antigen-induced changes in the proportion of antigen-binding cells expressing IgM, IgG, and IgD receptors.

Authors:  S Kanowith-Klein; E S Vitetta; E L Korn; R F Ashman
Journal:  J Immunol       Date:  1979-06       Impact factor: 5.422

3.  Surface immunoglobulins of lipopolysaccharide-stimulated spleen cells. The behavior of IgM, IgD and IgG.

Authors:  A Bourgois; K Kitajima; I R Hunter; B A Askonas
Journal:  Eur J Immunol       Date:  1977-03       Impact factor: 5.532

4.  Separate signals for human B cell proliferation and differentiation in response to Staphylococcus aureus: evidence for a two-signal model of B cell activation.

Authors:  R J Falkoff; L P Zhu; A S Fauci
Journal:  J Immunol       Date:  1982-07       Impact factor: 5.422

5.  Depletion of monocytes from human peripheral blood mononuclear leukocytes: comparison of the sephadex G-10 column method with other commonly used techniques.

Authors:  T R Jerrells; J H Dean; G L Richardson; R B Herberman
Journal:  J Immunol Methods       Date:  1980       Impact factor: 2.303

Review 6.  Separate signals for the initiation of proliferation and differentiation in the b cell response to antigen.

Authors:  R W Dutton
Journal:  Transplant Rev       Date:  1975

7.  Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes.

Authors:  B F Haynes; M E Hemler; D L Mann; G S Eisenbarth; J Shelhamer; H S Mostowski; C A Thomas; J L Strominger; A S Fauci
Journal:  J Immunol       Date:  1981-04       Impact factor: 5.422

8.  Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture.

Authors:  A Moretta; M C Mingari; B F Haynes; R P Sekaly; L Moretta; A S Fauci
Journal:  J Exp Med       Date:  1981-01-01       Impact factor: 14.307

9.  Activation of murine B lymphocytes by anti-immunoglobulin is an inductive signal leading to immunoglobulin secretion.

Authors:  D C Parker; D C Wadsworth; G B Schneider
Journal:  J Exp Med       Date:  1980-07-01       Impact factor: 14.307

10.  Frequency of B lymphocytes responsive to anti-immunoglobulin.

Authors:  A L Defranco; E S Raveche; R Asofsky; W E Paul
Journal:  J Exp Med       Date:  1982-05-01       Impact factor: 14.307
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Authors:  Hang Thi Thu Nguyen; Guillaume Dalmasso; Leif Torkvist; Jonas Halfvarson; Yutao Yan; Hamed Laroui; Doron Shmerling; Tiziano Tallone; Mauro D'Amato; Shanthi V Sitaraman; Didier Merlin
Journal:  J Clin Invest       Date:  2011-04-01       Impact factor: 14.808

Review 2.  Immunogenicity and immunochemistry of Streptococcus pneumoniae capsular polysaccharides.

Authors:  J E van Dam; A Fleer; H Snippe
Journal:  Antonie Van Leeuwenhoek       Date:  1990-06       Impact factor: 2.271

3.  Effect of recombinant human tumour necrosis factor beta (TNF beta) on activation, proliferation and differentiation of human B lymphocytes.

Authors:  H Zola; A Nikoloutsopoulos
Journal:  Immunology       Date:  1989-06       Impact factor: 7.397

4.  Modulation of human B cell responses by a monoclonal antibody to an activation antigen 4F2.

Authors:  T L Gerrard; C H Jurgensen; A S Fauci
Journal:  Clin Exp Immunol       Date:  1984-07       Impact factor: 4.330

5.  Regulation of human B-cell activation, proliferation, and differentiation by soluble factors.

Authors:  A Muraguchi; J H Kehrl; J L Butler; A S Fauci
Journal:  J Clin Immunol       Date:  1984-09       Impact factor: 8.317

6.  Responses of 'mature' human B lymphocyte lines to inducers of maturation and activation.

Authors:  H Zola; V Griffith; I Hunter; L Koh; J Bradley
Journal:  Clin Exp Immunol       Date:  1986-11       Impact factor: 4.330

7.  Antibody-secreting peripheral blood lymphocytes induced by immunization with a conjugate consisting of Streptococcus pneumoniae type 12F polysaccharide and diphtheria toxoid.

Authors:  C Lue; S J Prince; A Fattom; R Schneerson; J B Robbins; J Mestecky
Journal:  Infect Immun       Date:  1990-08       Impact factor: 3.441

8.  The Ly-10 antigen is a marker of mouse-activated T lymphocytes.

Authors:  M M Chan; U Hämmerling; O Stutman
Journal:  Immunogenetics       Date:  1988       Impact factor: 2.846

9.  4F2 monoclonal antibody recognizes a surface antigen on spread human fibroblasts of embryonic but not of adult origin.

Authors:  B Azzarone; H Suarez; M C Mingari; L Moretta; A S Fauci
Journal:  J Cell Biol       Date:  1984-03       Impact factor: 10.539
  9 in total

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