Literature DB >> 6187496

Tryptophan in the treatment of carcinoid crisis.

A L Harris, I E Smith.   

Abstract

A 56-year-old woman was admitted with carcinoid crisis and became comatose. Blood tryptophan at this stage was 5 micrograms/ml; after treatment with 3.4 g tryptophan daily her level of consciousness improved and blood tryptophan increased to 10 micrograms/ml. The carcinoid syndrome was not exacerbated by tryptophan. Tryptophan may have a supportive role in the management of carcinoid crisis.

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Year:  1983        PMID: 6187496     DOI: 10.1007/bf00446228

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN: 0344-5704            Impact factor:   3.333


  15 in total

Review 1.  THERAPY OF THE MALIGNANT CARCINOID SYNDROME.

Authors:  C E MENGEL
Journal:  Ann Intern Med       Date:  1965-03       Impact factor: 25.391

2.  Metabolic studies in carcinoid syndrome: observations on use of alpha-methyl DOPA, isonicotinic acid hydrazide and selective tryptophan deficiency.

Authors:  R B DAVIS; C S ALEXANDER; A ADICOFF
Journal:  Metabolism       Date:  1961-12       Impact factor: 8.694

3.  Free tryptophan in plasma and brain tryptophan metabolism.

Authors:  P J Knott; G Curzon
Journal:  Nature       Date:  1972-10-20       Impact factor: 49.962

4.  The malignant carcinoid syndrome.

Authors:  Z Davis; C G Moertel; D C McIlrath
Journal:  Surg Gynecol Obstet       Date:  1973-10

5.  The carcinoid syndrome: chronic treatment with para-chlorophenylalanine.

Authors:  W G Satterlee; A Serpick; J R Bianchine
Journal:  Ann Intern Med       Date:  1970-06       Impact factor: 25.391

Review 6.  Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine.

Authors:  A R Green; D G Grahame-Smith
Journal:  Nature       Date:  1976-04-08       Impact factor: 49.962

7.  Neutral amino acids in the brain: changes in response to food ingestion.

Authors:  J D Fernstrom; D V Faller
Journal:  J Neurochem       Date:  1978-06       Impact factor: 5.372

8.  Relationships between plasma, CSF and brain tryptophan.

Authors:  G Curzon
Journal:  J Neural Transm Suppl       Date:  1979

9.  Brain serotonin content: physiological dependence on plasma tryptophan levels.

Authors:  J D Fernstrom; R J Wurtman
Journal:  Science       Date:  1971-07-09       Impact factor: 47.728

10.  Studies of tryptophan and albumin metabolism in a patient with carcinoid syndrome, pellagra, and hypoproteinemia.

Authors:  C P Swain; A S Tavill; G Neale
Journal:  Gastroenterology       Date:  1976-09       Impact factor: 22.682

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  2 in total

Review 1.  Complications from carcinoid syndrome: review of the current evidence.

Authors:  José Mauricio Mota; Luana Guimarães Sousa; Rachel P Riechelmann
Journal:  Ecancermedicalscience       Date:  2016-08-08

Review 2.  Carcinoid Crisis: A Misunderstood and Unrecognized Oncological Emergency.

Authors:  Camilla Bardasi; Stefania Benatti; Gabriele Luppi; Ingrid Garajovà; Federico Piacentini; Massimo Dominici; Fabio Gelsomino
Journal:  Cancers (Basel)       Date:  2022-01-28       Impact factor: 6.639

  2 in total

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