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Literature DB >> 6187300

Studies on the immunologic aspects of keloids and hypertrophic scars.

Abstract

A significant difference between keloids and hypertrophic scars could be demonstrated by means of acid elution of lymphoid blood cells and immunofluorescence studies. A total of 20 patients (13 patients with keloids and seven with hypertrophic scars) were investigated. All the 13 patients with keloids revealed in the eluates antinuclear antibodies belonging to one or more of the five main classes and directed mainly against fibroblasts. On the other hand, there were no antinuclear antibodies detectable in the eluates of the seven patients with hypertrophic scars and in over 40 healthy controls.

Entities: Disease Species

Mesh：

Substances：

Year: 1982 PMID： 6187300 DOI： 10.1007/bf00403728

Source DB: PubMed Journal: Arch Dermatol Res ISSN： 0340-3696 Impact factor: 3.017

13 in total

1. The complement system in bullous pemphigoid. III. Fixation of C1q and C4 by pemphigoid antibody.

Authors: R E Jordon; J M Nordby; H Milstein
Journal: J Lab Clin Med Date: 1975-11

2. Pathologic scar formation. Morphologic and biochemical correlates.

Authors: T R Knapp; R J Daniels; E N Kaplan
Journal: Am J Pathol Date: 1977-01 Impact factor: 4.307

3. Cell size and growth characteristics of cultured fibroblasts isolated from normal and keloid tissue.

Authors: J D Russell; W S Witt
Journal: Plast Reconstr Surg Date: 1976-02 Impact factor: 4.730

4. Antibodies eluted from lymphoid cell membrane. Occurrence in certain varieties of scleroderma.

Authors: R H Cormane; F Hamerlinck; E Nunzi
Journal: Arch Dermatol Date: 1979-06

5. Collagen degradation in cultured keloid and hypertrophic scar tissue.

Authors: J P Milsom; R D Craig
Journal: Br J Dermatol Date: 1973-12 Impact factor: 9.302

6. Elution of antibodies from the lymphocyte membrane in certain dermatoses. Preliminary communication.

Authors: R H Cormane; F Hamerlinck; S Husz
Journal: Br J Dermatol Date: 1974-09 Impact factor: 9.302

7. The role of lymphoid cells and polymorphonuclear leukocytes in the pathogenesis of psoriasis.

Authors: R H Cormane; J Hunyadi; F Hamerlinck
Journal: J Dermatol Date: 1976-10 Impact factor: 4.005

8. Immunopathological studies on alopecia areata.

Authors: E Nunzi; F Hamerlinck; R H Cormane
Journal: Arch Dermatol Res Date: 1980 Impact factor: 3.017

9. Immunoglobulin-bearing lymphoid cells in primary syphilis. Quantitative and elution studies.

Authors: J D Bos; F Hamerlinck; R H Cormane
Journal: Br J Vener Dis Date: 1980-04

10. HLA antigens in keloids and hypertrophic scars.

Authors: G Laurentaci; D Dioguardi
Journal: Arch Dermatol Date: 1977-12

7 in total

Review 1. Aetiology and management of hypertrophic scars and keloids.

Authors: S T O'Sullivan; M O'Shaughnessy; T P O'Connor
Journal: Ann R Coll Surg Engl Date: 1996-05 Impact factor: 1.891

2. Anomalous expression of HLA class II molecules on keratinocytes and fibroblasts in hypertrophic scars consequent to thermal injury.

Authors: C Castagnoli; M Stella; G Magliacani; S T Alasia; P Richiardi
Journal: Clin Exp Immunol Date: 1990-11 Impact factor: 4.330