Literature DB >> 6186669

Inhibition of hyaluronidase by dextran sulfate and its possible application in anticancer treatment.

K Zimmermann, G Preinl, H Ludwig, K O Greulich.   

Abstract

Hyaluronidase is competitively inhibited by dextran sulfate. Hyaluronidase depolymerizes the amorphous component of the interstitial connective tissue and therefore supports tumor spread and metastasis. These processes may be reduced by dextran sulfate.

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Year:  1983        PMID： 6186669     DOI： 10.1007/bf00406931

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  15 in total

1.  TOXICITY OF HEPARINOIDS, WITH SPECIAL REFERENCE TO THE PRECIPITATION OF FIBRINOGEN.

Authors:  S SASAKI; T TAKEMOTO; S OKA
Journal:  Thromb Diath Haemorrh       Date:  1964-10-15

2.  Investigation of the toxicity of a series of dextran sulphates of varying molecular weight.

Authors:  K W WALTON
Journal:  Br J Pharmacol Chemother       Date:  1954-03

3.  Lymphosarcoma cell growth is selectively inhibited by B lymphocyte mitogens: LPS, dextran sulfate and PPD.

Authors:  P Ralph; I Nakoinz; W C Raschke
Journal:  Biochem Biophys Res Commun       Date:  1974-12-23       Impact factor: 3.575

4.  Collagenolytic activity in malignant melanoma: physiocochemical studies.

Authors:  Y Yamanishi; E Maeyens; M K Kabbous; H Ohyama; K Hashimoto
Journal:  Cancer Res       Date:  1973-10       Impact factor: 12.701

5.  Decrease of saturation density in cultured tumor cells by dextran sulfate.

Authors:  M Goto; Y Kataoka; H Sato
Journal:  Gan       Date:  1972-06

6.  Sulfation of dextran with piperidine-N-sulfonic acid.

Authors:  K Nagasawa; H Harada; S Hayashi; T Misawa
Journal:  Carbohydr Res       Date:  1972-03       Impact factor: 2.104

7.  A permeability-enhancing factor produced by tumor. The genesis of malignant effusions.

Authors:  R Stein-Werblowsky
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553

8.  Purification of hyaluronidase from human placenta.

Authors:  M Yamada; E Hasegawa; M Kanamori
Journal:  J Biochem       Date:  1977-02       Impact factor: 3.387

9.  Biological function of ascorbic acid and the pathogenesis of scurvy: a working hypothesis.

Authors:  E Cameron
Journal:  Med Hypotheses       Date:  1976 Jul-Aug       Impact factor: 1.538

10.  On the prevention of haematogenous tumor metastases rats. The role of the proteinase inhibitor "Trasylol".

Authors:  R Stein-Werblowsky
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553
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  2 in total

1.  Inhibition of hyaluronan degradation by dextran sulphate facilitates characterisation of hyaluronan synthesis: an in vitro and in vivo study.

Authors:  Lishanthi Udabage; Gary R Brownlee; Robert Stern; Tracey J Brown
Journal:  Glycoconj J       Date:  2004       Impact factor: 2.916

2.  Expression of hyaluronidase by tumor cells induces angiogenesis in vivo.

Authors:  D Liu; E Pearlman; E Diaconu; K Guo; H Mori; T Haqqi; S Markowitz; J Willson; M S Sy
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-23       Impact factor: 11.205
  2 in total

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