| Literature DB >> 6185423 |
Abstract
High-molecular-weight polysaccharide from Pseudomonas aeruginosa immunotypes 1 and 2 gave cross-protection in outbred CD-1 mice challenged with the heterologous immunotype organism. Both active immunization with 50 micrograms of polysaccharide, as well as passive transfer of immune serum were effective. The basis for this cross-protection is the ability of high doses of polysaccharide to induce antibody formation to both homologous and heterologous immunotype determinants.Entities:
Mesh:
Substances:
Year: 1982 PMID: 6185423 PMCID: PMC347865 DOI: 10.1128/iai.38.3.1117-1122.1982
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441