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Literature DB >> 6185417

Gene(s) affecting the expression of Qa-1.

Abstract

Lymphocytes from different strains vary in their expression of antigenic determinants encoded by the Qa1 locus. Thus, a lower percentage of cells from strains bearing H-2Dk are lysed in antibody-mediated cytotoxic tests. These cells fail to completely absorb anti-Qa1 activity from antisera. The unexpressed determinants are present in unactivated cells when subcellular fractions are tested and are detectable on the membrane of mitogen-activated lymphocytes. The gene(s) controlling this phenomenon are dominant and map to a region between H-2S and Tla.

Entities: Gene

Mesh：

Substances：

Year: 1982 PMID： 6185417 DOI： 10.1007/bf00372102

Source DB: PubMed Journal: Immunogenetics ISSN： 0093-7711 Impact factor: 2.846

11 in total

1. Turnover of the plasma membrane proteins of hepatoma tissue culture cells.

Authors: J Tweto; D Doyle
Journal: J Biol Chem Date: 1976-02-10 Impact factor: 5.157

2. An approach to the mapping of antigens on the cell surface.

Authors: E A Boyse; L J Old; E Stockert
Journal: Proc Natl Acad Sci U S A Date: 1968-07 Impact factor: 11.205

3. Surface mapping of mouse thymocytes.

Authors: L Flaherty; D Zimmerman
Journal: Proc Natl Acad Sci U S A Date: 1979-04 Impact factor: 11.205

4. Recognition of alternate alleles and mapping of the Qa1 locus.

Authors: T H Stanton; S Carbon; M Maynard
Journal: J Immunol Date: 1981-10 Impact factor: 5.422

5. Qat-4 and Qat-5, new murine T-cell antigens governed by the Tla region and identified by monoclonal antibodies.

Authors: G J Hämmerling; U Hämmerling; L Flaherty
Journal: J Exp Med Date: 1979-07-01 Impact factor: 14.307

6. New complexities at the Qa-1 locus.

Authors: L Flaherty; E Rinchik; K DiBiase
Journal: Immunogenetics Date: 1981 Impact factor: 2.846

7. Quantitative variation in H-2-antigen expression. I. Estimation of H-2K and H-2D expression in different strains of mice.

Authors: H C O'Neill; I F McKenzie
Journal: Immunogenetics Date: 1980 Impact factor: 2.846

8. Alterations in the expression of Ia antigens in F1 hybrid mice.

Authors: M S Sandrin; G H Tobias; I F McKenzie; G J Hämmerling
Journal: Immunogenetics Date: 1981-12 Impact factor: 2.846

9. Induction of resistance to antibody-mediated cytotoxicity. H-2, Ia, and Ig antigens are independent entities in the membrane of mouse lymphocytes.

Authors: V Hauptfeld; M Hauptfeld; J Klein
Journal: J Exp Med Date: 1975-05-01 Impact factor: 14.307

Review 4. Towards Clinical Translation of CD8⁺ Regulatory T Cells Restricted by Non-Classical Major Histocompatibility Complex Ib Molecules.

Authors: Samiksha Wasnik; David J Baylink; Jianmei Leavenworth; Chenfan Liu; Hongzheng Bi; Xiaolei Tang
Journal: Int J Mol Sci Date: 2019-09-28 Impact factor: 5.923

5. The class I-b molecule Qa-1 forms heterodimers with H-2Ld and a novel 50-kD glycoprotein encoded centromeric to I-E beta.

Authors: P R Wolf; R G Cook
Journal: J Exp Med Date: 1995-02-01 Impact factor: 14.307

5 in total

Gene(s) affecting the expression of Qa-1.

1. Turnover of the plasma membrane proteins of hepatoma tissue culture cells.

2. An approach to the mapping of antigens on the cell surface.

3. Surface mapping of mouse thymocytes.

4. Recognition of alternate alleles and mapping of the Qa1 locus.

5. Qat-4 and Qat-5, new murine T-cell antigens governed by the Tla region and identified by monoclonal antibodies.

6. New complexities at the Qa-1 locus.

7. Quantitative variation in H-2-antigen expression. I. Estimation of H-2K and H-2D expression in different strains of mice.

8. Alterations in the expression of Ia antigens in F1 hybrid mice.

9. Induction of resistance to antibody-mediated cytotoxicity. H-2, Ia, and Ig antigens are independent entities in the membrane of mouse lymphocytes.

10. Isoantigens of the H-2 and Tla loci of the mouse: interactions affecting their representation on thymocytes.

1. CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice.

2. A new determinant, Qa-m208, detected on T lymphocytes and transfected L cells by a Kb-specific monoclonal antibody.

3. T cell vaccination induces T cell receptor Vbeta-specific Qa-1-restricted regulatory CD8(+) T cells.

Review 4. Towards Clinical Translation of CD8⁺ Regulatory T Cells Restricted by Non-Classical Major Histocompatibility Complex Ib Molecules.

5. The class I-b molecule Qa-1 forms heterodimers with H-2Ld and a novel 50-kD glycoprotein encoded centromeric to I-E beta.

Review 4. Towards Clinical Translation of CD8+ Regulatory T Cells Restricted by Non-Classical Major Histocompatibility Complex Ib Molecules.

Review 4. Towards Clinical Translation of CD8⁺ Regulatory T Cells Restricted by Non-Classical Major Histocompatibility Complex Ib Molecules.