Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A new determinant, Qa-m208, detected on T lymphocytes and transfected L cells by a Kb-specific monoclonal antibody.

Literature DB >> 6329949

A new determinant, Qa-m208, detected on T lymphocytes and transfected L cells by a Kb-specific monoclonal antibody.

M Oudshoorn-Snoek, A L Mellor, R A Flavell, P Démant.

Abstract

A Kb-specific monoclonal antibody, 6.3.4, defining a new class I specificity, m208, reacts with some K and D region products and with a Qa determinant present on T lymphocytes but not detectable on thymocytes and B lymphocytes. The strain distribution of reactions indicates that this determinant is controlled by the Qa-Tla region, and shows no concordance with the strain distribution pattern of any of the known Qa antigens. The antibody reacts also with L cells expressing a cloned H-2b class I gene mapping in the Qa-Tla region.

Mesh：

Substances：

Year: 1984 PMID： 6329949 DOI： 10.1007/bf00403437

Source DB: PubMed Journal: Immunogenetics ISSN： 0093-7711 Impact factor: 2.846

40 in total

1. Molecular heterogeneity of D-end products detected by anti-H-2.28 sera. III. Reactivity of certain anti-H-2.28 alloantisera with Qa-2 antigen.

Authors: D Iványi; M Cherry; P Démant
Journal: Immunogenetics Date: 1982 Impact factor: 2.846

2. Molecular heterogeneity of D-end products detected by anti-H-2.28 sera. I. A. molecule similar to Qa-2, detected in the BALB/cBy but not in the BALB/c-H-2dm2 mutant.

Authors: P Démant; M H Roos
Journal: Immunogenetics Date: 1982 Impact factor: 2.846

3. Comparison of nucleotide sequences of mRNAs belonging to the mouse H-2 multigene family.

Authors: J L Lalanne; F Bregegere; C Delarbre; J P Abastado; G Gachelin; P Kourilsky
Journal: Nucleic Acids Res Date: 1982-02-11 Impact factor: 16.971

4. Primary structural studies of the Qa-2 alloantigen: implications for the evolution of the MHC.

Authors: M J Soloski; J W Uhr; E S Vitetta
Journal: Nature Date: 1982-04-22 Impact factor: 49.962

5. Qualitative and quantitative aspects of anti-H-2Ld sera.

Authors: M Oudshoorn-Snoek; D Iványi; P Démant
Journal: Transplantation Date: 1981-08 Impact factor: 4.939

6. Qat-4 and Qat-5, new murine T-cell antigens governed by the Tla region and identified by monoclonal antibodies.

Authors: G J Hämmerling; U Hämmerling; L Flaherty
Journal: J Exp Med Date: 1979-07-01 Impact factor: 14.307

7. Syngeneic tumor immunizations produce Qa antibodies. Discovery of a new Qa antigen, Qa-6.

Authors: L Flaherty; M Karl; C L Reinisch
Journal: Immunogenetics Date: 1982 Impact factor: 2.846

8. Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer.

Authors: R S Goodenow; M McMillan; M Nicolson; B T Sher; K Eakle; N Davidson; L Hood
Journal: Nature Date: 1982-11-18 Impact factor: 49.962

9. Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex.

Authors: A Winoto; M Steinmetz; L Hood
Journal: Proc Natl Acad Sci U S A Date: 1983-06 Impact factor: 11.205

8. Expression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens.

Authors: I Stroynowski; J Forman; R S Goodenow; S G Schiffer; M McMillan; S O Sharrow; D H Sachs; L Hood
Journal: J Exp Med Date: 1985-05-01 Impact factor: 14.307

8 in total

A new determinant, Qa-m208, detected on T lymphocytes and transfected L cells by a Kb-specific monoclonal antibody.

1. Molecular heterogeneity of D-end products detected by anti-H-2.28 sera. III. Reactivity of certain anti-H-2.28 alloantisera with Qa-2 antigen.

2. Molecular heterogeneity of D-end products detected by anti-H-2.28 sera. I. A. molecule similar to Qa-2, detected in the BALB/cBy but not in the BALB/c-H-2dm2 mutant.

3. Comparison of nucleotide sequences of mRNAs belonging to the mouse H-2 multigene family.

4. Primary structural studies of the Qa-2 alloantigen: implications for the evolution of the MHC.

5. Qualitative and quantitative aspects of anti-H-2Ld sera.

6. Qat-4 and Qat-5, new murine T-cell antigens governed by the Tla region and identified by monoclonal antibodies.

7. Syngeneic tumor immunizations produce Qa antibodies. Discovery of a new Qa antigen, Qa-6.

8. Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer.

9. Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex.

10. Molecular similarities between the Qa-2 alloantigen and other gene products of the 17th chromosome of the mouse.

1. Analysis of the Qa-4 allodeterminant.

2. Characterization of a Q subregion gene in the murine major histocompatibility complex.

3. Interaction between Kb and Q4 gene sequences generates the Kbm6 mutation.

4. NH2-terminal amino acid sequence analysis of Qa-2 alloantigens.

5. Qa alloantigen expression on functional T lymphocytes from spleen and thymus.

6. Five serologically distinguishable Dq region molecules.

7. H-2 class I antigen expression on mouse teratocarcinoma cell lines.

8. Expression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens.