Literature DB >> 6184041

Intraocular antiviral penetration.

R H Poirier, J D Kingham, P de Miranda, M Annel.   

Abstract

Aqueous levels of topically applied vidarabine monophosphate, trifluridine, and acyclovir were determined following topical administration in patients with normal corneas prior to cataract extraction. Meager levels in aqueous were found for vidarabine monophosphate, and none for trifluridine. Substantial levels of acyclovir were detected that were well within the therapeutic range of herpes simplex susceptibility.

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Year:  1982        PMID: 6184041     DOI: 10.1001/archopht.1982.01030040944016

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  14 in total

1.  Clinical evaluation of carbocyclic oxetanocin G eyedrops in the treatment of herpes simplex corneal ulcers.

Authors:  H Shiota; K Nitta; T Naito; Y Mimura; T Maruyama
Journal:  Br J Ophthalmol       Date:  1996-05       Impact factor: 4.638

2.  A comparison of local and systemic acyclovir in the management of herpetic disciform keratitis.

Authors:  S M Porter; A Patterson; P Kho
Journal:  Br J Ophthalmol       Date:  1990-05       Impact factor: 4.638

3.  Ocular herpes simplex virus infections: reduced sensitivity to acyclovir in primary disease.

Authors:  S J Charles; J J Gray
Journal:  Br J Ophthalmol       Date:  1990-05       Impact factor: 4.638

4.  Clinical characteristics of acyclovir-resistant herpetic keratitis and experimental studies of isolates.

Authors:  Y F Yao; Y Inoue; T Kase; Y Uchihori; Y Mori; Y Ohashi
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1996-08       Impact factor: 3.117

Review 5.  Ocular surgery after herpes simplex and herpes zoster keratitis.

Authors:  Piotr Kanclerz; Jorge L Alio
Journal:  Int Ophthalmol       Date:  2020-09-10       Impact factor: 2.031

6.  Pharmacokinetics of oral acyclovir (Zovirax) in the eye.

Authors:  S O Hung; A Patterson; P J Rees
Journal:  Br J Ophthalmol       Date:  1984-03       Impact factor: 4.638

7.  Randomised double-blind trial of acyclovir (Zovirax) and adenine arabinoside in herpes simplex amoeboid corneal ulceration.

Authors:  L M Collum; P Logan; D McAuliffe-Curtin; S O Hung; A Patterson; P J Rees
Journal:  Br J Ophthalmol       Date:  1985-11       Impact factor: 4.638

Review 8.  Rational acyclovir therapy in herpetic eye disease.

Authors:  M G Falcon
Journal:  Br J Ophthalmol       Date:  1987-02       Impact factor: 4.638

9.  Double-masked trial of topical acyclovir and steroids in the treatment of herpes zoster ocular inflammation.

Authors:  R J Marsh; M Cooper
Journal:  Br J Ophthalmol       Date:  1991-09       Impact factor: 4.638

10.  Acyclovir ointment plus topical betamethasone or placebo in first episode disciform keratitis.

Authors:  W J Power; M P Hillery; A Benedict-Smith; L M Collum
Journal:  Br J Ophthalmol       Date:  1992-12       Impact factor: 4.638

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