Literature DB >> 6182472

Primary structure of alpha-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence.

M Noda, H Takahashi, T Tanabe, M Toyosato, Y Furutani, T Hirose, M Asai, S Inayama, T Miyata, S Numa.   

Abstract

DNA sequences complementary to the Torpedo californica electroplax mRNA coding for the alpha-subunit precursor of the acetylcholine receptor were cloned. The nucleotide sequence of the cloned cDNA indicates that the precursor consists of 461 amino acids including a prepeptide of 24 amino acids. Possible sites for acetylcholine binding and antigenic determinants on the alpha-subunit molecule are discussed.

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Year:  1982        PMID: 6182472     DOI: 10.1038/299793a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  138 in total

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7.  Homology modeling and molecular dynamics simulations of transmembrane domain structure of human neuronal nicotinic acetylcholine receptor.

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Review 8.  Myasthenia gravis--current concepts.

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10.  Altered patterns of N-linked glycosylation of the Torpedo acetylcholine receptor expressed in Xenopus oocytes.

Authors:  A L Buller; M M White
Journal:  J Membr Biol       Date:  1990-05       Impact factor: 1.843

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