Literature DB >> 6180303

Properties of dispersed, highly repeated DNA within and near the hamster CAD gene.

R A Padgett, G M Wahl, G R Stark.   

Abstract

Dispersed, highly repeated DNA sequences were found within and near the Syrian hamster gene coding for the multifunctional protein CAD. Most of the repeated sequences were homologous to each other and had similar properties. They hybridized to many cytoplasmic polyadenylated RNAs and to 7S and 4.5S cytoplasmic non-polyadenylated RNAs. Cloned DNA fragments containing repeated sequences were transcribed in vitro by RNA polymerase III. The repeated sequences from Syrian hamsters share many properties with the Alu family of repetitive DNA from humans. The hamster sequences were homologous to total repetitive human DNA but only very weakly homologous to two cloned members of the human Alu family.

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Year:  1982        PMID： 6180303      PMCID： PMC369789          DOI： 10.1128/mcb.2.3.302-307.1982

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  21 in total

1.  Comparative aspects of DNA organization in Metazoa.

Authors:  E H Davidson; G A Galau; R C Angerer; R J Britten
Journal:  Chromosoma       Date:  1975-07-21       Impact factor: 4.316

2.  Intermolecular duplexes in heterogeneous nuclear RNA from HeLa cells.

Authors:  N Fedoroff; P K Wellauer; R Wall
Journal:  Cell       Date:  1977-04       Impact factor: 41.582

3.  Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

Authors:  G M Wahl; M Stern; G R Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

4.  Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells.

Authors:  G M Wahl; R A Padgett; G R Stark
Journal:  J Biol Chem       Date:  1979-09-10       Impact factor: 5.157

5.  Comparison of oligonucleotides produced by RNase T1 digestion of 7 S RNA from avian and murine oncornaviruses and from uninfected cells.

Authors:  E Erikson; R L Erikson; B Henry; N R Pace
Journal:  Virology       Date:  1973-05       Impact factor: 3.616

6.  Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes.

Authors:  J C Alwine; D J Kemp; G R Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

7.  Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.

Authors:  R J Britten; D E Kohne
Journal:  Science       Date:  1968-08-09       Impact factor: 47.728

8.  N-(Phosphonacetyl)-L-aspartate-resistant hamster cells overaccumulate a single mRNA coding for the multifunctional protein that catalyzes the first steps of UMP synthesis.

Authors:  R A Padgett; G M Wahl; P F Coleman; G R Stark
Journal:  J Biol Chem       Date:  1979-02-10       Impact factor: 5.157

9.  Series of 4.5S RNAs associated with poly(A)-containing RNAs of rodent cells.

Authors:  F Harada; N Kato; H Hoshino
Journal:  Nucleic Acids Res       Date:  1979-10-25       Impact factor: 16.971

10.  Low molecular weight RNAs hydrogen-bonded to nuclear and cytoplasmic poly(A)-terminated RNA from cultured Chinese hamster ovary cells.

Authors:  W Jelinek; L Leinwand
Journal:  Cell       Date:  1978-09       Impact factor: 41.582
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  8 in total

1.  Localization of amplified CAD genes on rearranged chromosomes of Chinese hamster cells.

Authors:  L Ottaggio; C Agnese; S Bonatti; P Cavolina; A Di Leonardo; M Miele; A Abbondandolo
Journal:  Cytotechnology       Date:  1987-10       Impact factor: 2.058

2.  Sequence organization and developmental expression of an interspersed, repetitive element and associated single-copy DNA sequences in Dictyostelium discoideum.

Authors:  A R Kimmel; R A Firtel
Journal:  Mol Cell Biol       Date:  1985-08       Impact factor: 4.272

3.  Structure of the gene for CAD, the multifunctional protein that initiates UMP synthesis in Syrian hamster cells.

Authors:  R A Padgett; G M Wahl; G R Stark
Journal:  Mol Cell Biol       Date:  1982-03       Impact factor: 4.272

4.  The 3' untranslated regions of two related mRNAs contain an element highly repeated in the sea urchin genome.

Authors:  C D Carpenter; A M Bruskin; L M Spain; E D Eldon; W H Klein
Journal:  Nucleic Acids Res       Date:  1982-12-11       Impact factor: 16.971

5.  General method for cloning amplified DNA by differential screening with genomic probes.

Authors:  O Brison; F Ardeshir; G R Stark
Journal:  Mol Cell Biol       Date:  1982-05       Impact factor: 4.272

6.  Homologous recombination in mammalian cells mediates formation of a functional gene from two overlapping gene fragments.

Authors:  B R de Saint Vincent; G M Wahl
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

7.  Single-copy and amplified CAD genes in Syrian hamster chromosomes localized by a highly sensitive method for in situ hybridization.

Authors:  G M Wahl; L Vitto; R A Padgett; G R Stark
Journal:  Mol Cell Biol       Date:  1982-03       Impact factor: 4.272

8.  Structure of DNA formed in the first step of CAD gene amplification.

Authors:  E Giulotto; I Saito; G R Stark
Journal:  EMBO J       Date:  1986-09       Impact factor: 11.598
  8 in total

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